Compare Abilify vs. Ativan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Abilify
(aripiprazole)

Ativan
(lorazepam)

Helps control your thoughts and mood. Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.Helps you relax. Ativan (lorazepam) is an effective medicine for occasional or short-term anxiety. It's less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.29Abilify
Reviews for Abilify
44%
of people (All ages) say Abilify is worth it
40%
say it works well
34%
say it's a big hassle
252 reviews
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it
Reviews for Ativan
71%
-27% worse vs. Abilify
51%
-11% worse vs. Abilify
15%
-19% worse vs. Abilify
642 reviews
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it
Side effects
AbilifyAtivan
  • Sleepiness 20%
  • Difficulty controlling movements 17%
  • Fatigue 7%
  • Nausea 7%
  • Restlessness 8%
  • Blurred vision 8%
  • Excess drooling 6%
  • Dizziness 4%
  • Extreme restlessness 21%
  • Insomnia 6%
More Abilify side effects »
  • Sleepiness 16%
  • Dizziness 7%
  • Weakness 4%
  • Unsteadiness 3%
More Ativan side effects »
How it works
AbilifyAtivan
Abilify (aripiprazole) is an atypical antipsychotic. It stabilizes dopamine and serotonin levels in your brain to help control your thoughts and affect mood.Ativan (lorazepam) is a fast-acting benzodiazepine. It affects areas of the brain that help calm you down. This reduces anxiety and can cause sleepiness.
Type of medication
AbilifyAtivan
Prescription onlyPrescription only
Available as
AbilifyAtivan
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
  • Pill
  • Liquid
  • Injection
Used for
AbilifyAtivan
Risk factors for serious side effects
AbilifyAtivan
  • Elderly patients with dementia
  • Age 24 years or younger
  • Use of antidepressant medications
  • People with diabetes
  • People with high cholesterol
Detailed Abilify (aripiprazole) risks & warnings »
  • Taking with opioids
  • Taking more than the prescribed dose
  • Taking Ativan (lorazepam) for longer than 4 weeks
  • History of drug abuse
  • Long-term use
Detailed Ativan (lorazepam) risks & warnings »
Pregnancy
Interactions
AbilifyAtivan
No interactions related info.
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
Alcohol
AbilifyAtivan
No alcohol related info.
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
Sleep
AbilifyAtivan
No sleep related info.
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
Weight
AbilifyAtivan
  • Abilify (aripiprazole) can make you gain weight, which can also increase your blood sugar and cholesterol. If you're at risk for diabetes, high blood pressure or high cholestetrol, talk to your doctor how to lower your risk.
No weight related info.
Upsides and benefits
AbilifyAtivan
  • Effective at relieving psychotic symptoms and manic episodes.
  • More energizing than other antipsychotics.
  • Fewer side effects than other antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
  • Effective at relieving short-term anxiety.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in.
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
Downsides and risks
AbilifyAtivan
  • Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
  • Compared to other similar medicines, Ativan (lorazepam) is more likely to cause withdrawal if you take it for a long time and then suddenly stop.
  • Most people find that Ativan (lorazepam) gets less effective over time.
Tips from our pharmacists for people taking the medication
AbilifyAtivan
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Makes you energized. Take in the morning to avoid difficulty sleeping.
  • For the first week, avoid activities that require you to be alert.
  • May increase cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Available in pills that you take daily, and as a monthly injection.
  • Can cause temporary dizziness and drowsiness.
  • Take only as much as your doctor prescribes. Taking more than directed or taking this for a long time can cause you to become dependent on it.
  • Not safe to use with alcohol.
  • Use caution or avoid use in older adults.
Learn more
More about AbilifySide effectsReviews & ratingsAlternativesFDA package insert
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it
More about AtivanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it