Compare Abilify vs. fluphenazine decanoate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Abilify
(aripiprazole)

Prolixin Decanoate
(fluphenazine decanoate)

Helps control your thoughts and mood. Abilify (Aripiprazole) is good for treating psychosis and mania, and can help with depression. Less likely to cause side effects than any other antipsychotic, but has a risk of suicidal thoughts for people age 24 and younger.Treats schizophrenia or psychosis. Prolixin Decanoate (fluphenazine decanoate) is long-acting medicine for stabilizing your mood that must be given by a trained healthcare professional.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Abilify
Best available price for 30 (5mg) tablets of aripiprazole
No pricing data for this drug at this filter setting. Try searching onGoodRx
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.29Abilify
Reviews for Abilify (aripiprazole)
44%
of people (All ages) say Abilify (aripiprazole) is worth it
40%
say it works well
34%
say it's a big hassle
252 reviews
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it
Reviews for Prolixin Decanoate (fluphenazine decanoate)
Not enough review data. Review it!
-44% worse vs. Abilify (aripiprazole)
Not enough review data. Review it!
-40% worse vs. Abilify (aripiprazole)
Not enough review data. Review it!
+34% better vs. Abilify (aripiprazole)
Have you used Prolixin Decanoate (fluphenazine decanoate)?
Worth itNot sureNot worth it
Side effects
Abilifyfluphenazine decanoate
  • Headache 4%
  • Agitation 2%
  • Sleep difficulty 5%
  • Anxiety 4%
  • Nausea 4%
  • Restlessness 9%
  • Constipation 4%
  • Vomiting 5%
  • Dizziness 3%
  • Indigestion 2%
More Abilify side effects »

The fluphenazine decanoate FDA package insert doesn’t have numbers about how common side effects are.

More about fluphenazine decanoate side effects »
How it works
Abilifyfluphenazine decanoate
Abilify (Aripiprazole) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.Prolixin Decanoate (fluphenazine decanoate) is a derivative of phenothiazine. It regulates dopamine levels in your brain to control psychotic episodes or schizophrenia.
Type of medication
Abilifyfluphenazine decanoate
Prescription only
Prescription only
Available as
Abilifyfluphenazine decanoate
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
  • Injection
Used for
Abilifyfluphenazine decanoate
Risk factors for serious side effects
Abilifyfluphenazine decanoate
  • Elderly patients with dementia
  • Age 24 years or younger
  • History of heart problems
  • Drug interactions
  • People with diabetes
Detailed Abilify (aripiprazole) risks & warnings »
  • People over 65 with dementia and psychosis
  • Taking antipsychotic medications
Detailed Prolixin Decanoate (fluphenazine decanoate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
Abilifyfluphenazine decanoate
No alcohol related info.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
Sleep
Abilifyfluphenazine decanoate
No sleep related info.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
Weight
Abilifyfluphenazine decanoate
  • Least likely antipsychotic to cause weight gain.
  • Abilify (Aripiprazole) can cause you to gain weight. Abilify (Aripiprazole) is the least likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
No weight related info.
Upsides and benefits
Abilifyfluphenazine decanoate
  • Effective at relieving psychotic symptoms and manic episodes. All antipsychotic medicines are about equally effective.
  • More energizing than other antipsychotics.
  • Fewer side effects than any other antipsychotics.
  • Least likely antipsychotic to cause weight gain.
  • Less likely to cause heart problems compared to some antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
  • Can be given less frequently than the oral, short-acting version.
  • Available in generic.
Downsides and risks
Abilifyfluphenazine decanoate
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • Can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can only be used if you're already stable on the short-acting version of this medicine.
Tips from our pharmacists for people taking the medication
Abilifyfluphenazine decanoate
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Makes you energized. Take in the morning to avoid difficulty sleeping.
  • For the first week, avoid activities that require you to be alert.
  • May worsen cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Elderly people with dementia shouldn't take it.
  • Can make you more sensitive to the sun, so wear sunscreen or protective clothing while outside.
  • Can affect how your body regulates your temperature, so drink plenty of liquids especially when you're exercising.
  • Can make it difficult for you to start and stop your movements. Talk to your doctor right away if this happens.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
Learn more
More about AbilifySide effectsReviews & ratingsAlternativesFDA package insert
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it
More about fluphenazine decanoateSide effectsAlternativesFDA package insert
Have you used Prolixin Decanoate (fluphenazine decanoate)?
Worth itNot sureNot worth it