Compare Aciphex vs. Prevacid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aciphex (Rabeprazole)

Prescription only

Prevacid (lansoprazole)

Prescription or OTC
Treats heartburn and ulcers.

Aciphex (Rabeprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.

Treats heartburn and stomach ulcers.

Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers.

5.5/ 7 average rating with 21 reviewsforPrevacid
Upsides
  • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
  • Lasts longer than other similar stomach medicines. Most people take it once a day.
  • Your body won't develop a tolerance to Aciphex (Rabeprazole), so it'll work the same way as long as you need to keep taking it.
  • Once heartburn symptoms are treated, a low dose of Aciphex (Rabeprazole) can be taken daily.
  • Most people can take Prevacid (lansoprazole) without any noticeable day-to-day side effects.
  • Comes in a dissolving tablet to be placed on the tongue if you cannot or do not like to swallow pills.
  • Prevacid (lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
Downsides
  • Taking Aciphex (Rabeprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
  • Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • There's no generic version available, so it can be expensive.
  • Doesn't start working right away like some other acid reducers (Tums, Rolaids, or Maalox).
  • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and C. diff infection (bacterial).
  • Is used if you have frequent heartburns that occur more than 2 days per week. Speak to your doctor or pharmacist if you only have occasional heartburn.
Used for
Dosage forms
  • Extended release
  • Extended release
  • Dissolving tablet extended release
  • Liquid
Price
Lowest price near you
$544.34
Find instant savings
Lowest price near you
$17.45
Find instant savings
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
Not enough review data.Leave a review
21 
71%
think this treatment is worth it
71%
think this treatment works well
19%
think this treatment is a hassle

Have you used Prevacid (lansoprazole)?

Leave a review
Side effects
7possible side effects
  • Headache
    10%
  • Diarrhea
    5%
  • Nausea
    5%
  • Abdominal pain
    5%
  • Vomiting
    4%
  • Pain
    3%
  • Pharyngitis
    3%
See more detailed side effects
2possible side effects
  • Diarrhea
    4%
  • Abdominal pain
    2%
See more detailed side effects
Risks and warnings
  • Severe stomach inflammation (atrophic gastritis)

    Helicobacter pylori infection

    ...and 1 more risk factors

  • Severe diarrhea

    Being hospitalized

    ...and 1 more risk factors

  • Broken bones

    Osteoporosis

    ...and 5 more risk factors

See more detailed risks and warnings
  • Bone fractures

    High dose Prevacid (lansoprazole)

    ...and 3 more risk factors

See more detailed risks and warnings