Compare Aciphex vs. Tagamet
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats heartburn and ulcers.
Aciphex (Rabeprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.
Tagamet (cimetidine) works well for heartburn, but may have more side effects than other medicines like it.
3.4/ 5 average rating with 632 reviewsforTagamet
- Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
- Lasts longer than other similar stomach medicines. Most people take it once a day.
- Your body won't develop a tolerance to Aciphex (Rabeprazole), so it'll work the same way as long as you need to keep taking it.
- Once heartburn symptoms are treated, a low dose of Aciphex (Rabeprazole) can be taken daily.
- Lasts longer than other medicines like it so you may not need to take it as frequently.
- Affordable as an over-the-counter or generic medicine.
- Taking Aciphex (Rabeprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
- Many drugs can interact with Aciphex (Rabeprazole), so talk to your doctor or pharmacist before starting any new medicines.
- There's no generic version available, so it can be expensive.
- Does not work as fast as antacids like Maalox, Tums, or Rolaids.
- May not work as well if you have an inflammed esophagus. Your doctor will assess which medicine is best for you.
- May not be the best option if you are elderly or have kidney or liver problems.
- Can interfere with how other medicines work.
- Extended release
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10possible side effects
- Abdominal pain5%
The Tagamet (cimetidine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Hiding possible cancer
- Severe stomach inflammation (atrophic gastritis)
- Helicobacter pylori infection
- Autoimmune disease
- Severe diarrhea
- Being hospitalized
- Antibiotic use
- Broken bones
- Age 50 or older
- Using high medication doses
- Long-term therapy (1 year or more)
- Use of other medications that weaken bones
- Low vitamin or mineral levels
- Kidney problems
- Liver problems
- Drug interactions
- Chronic lung problems
- Lung problems
- Clostridium difficile associated diarrhea
- Taking antibiotics
- Englarged breasts in men (gynecomastia)