Compare Actos vs. Glucotrol
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.
Glucotrol (glipizide) is an effective medicine for lowering blood sugar, but it can cause your blood sugar level to be too low so you must always carry some form of sugar with you that can be readily used.
- Improves sugar control and lowers A1c levels by around 1%.
- Easily taken by mouth as a once a day pill.
- Prevents the harmful effects of high sugar levels on your organs.
- Rarely causes low blood sugar.
- Lower the risk of heart attack or stroke.
- Lowers A1c levels by 1-2%.
- Glucotrol (glipizide) is an oral medicine so it might be a good alternative for those who don't like injections.
- Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
- Okay to use by people with kidney problems.
- Available as a generic form and is relatively cheap.
- May take several weeks to lower blood sugar.
- Can cause weight gain.
- People with heart failure or history of bladder cancer shouldn't use this medicine.
- Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
- Raises the risk of bone fractures, especially for people who already have a risk for fractures.
- Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
- While taking Glucotrol (glipizide), your blood sugars should be checked 2 to 5 times a week, but less often once you are on a stable dose.
- Can cause mild weight gain of 2-3lb.
- Might lose its effectiveness over time.
- Needs to be taken 30 minutes before a meal for it to be most effective.
- Extended release pill
Have you used Actos (pioglitazone)?Leave a review
- Low blood sugar27%
- Colds and flu13%
- Heart failure8%
- Sinus infection6%
- Back pain6%
- Pain in arms and legs6%
- Muscle pain5%
- Sore throat5%
- Low blood sugar3%
- Passing gas3%
- Heart failure
- Liver damage
Current liver problems
- Bladder cancer
History of bladder cancer
- Bone fracture
- Low blood sugar
Skipping meals or having inconsistent meal times
...and 4 more risk factors
- Severe allergic reaction
History of allergy to sulfa-containing medicine
- Kidney and liver disease
Those with kidney and/or liver disease
- Breakdown of red blood cells
People with G6PD deficiency