Compare Actos vs. Glucovance
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.
Glyburide / Metformin is an effective combination medicine for lowering blood sugar, but it is likely to cause diarrhea in the first few weeks.
- Improves sugar control and lowers A1c levels by around 1%.
- Easily taken by mouth as a once a day pill.
- Prevents the harmful effects of high sugar levels on your organs.
- Rarely causes low blood sugar.
- Lower the risk of heart attack or stroke.
- Glyburide / Metformin effectively lowers blood sugar levels more so than if each of the individual medicines it contains are taken alone.
- Protects your organs and blood vessels from the harmful effects of high blood sugar levels.
- Can potentially lower your "bad cholesterol" levels.
- Glyburide / Metformin is available in a generic form and is cheaper than many other combination diabetes medicines.
- May take several weeks to lower blood sugar.
- Can cause weight gain.
- People with heart failure or history of bladder cancer shouldn't use this medicine.
- Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
- Raises the risk of bone fractures, especially for people who already have a risk for fractures.
- Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
- Glyburide / Metformin is likely to cause nausea, stomach upset, or diarrhea in the first few weeks.
- Not a good treatment option for those with kidney and/or liver problems.
- Drinking large amounts of or frequently using alcohol while taking Glyburide / Metformin can cause harm to your body.
- Can cause some weight gain.
Have you used Actos (pioglitazone)?Leave a review
- Low blood sugar27%
- Colds and flu13%
- Heart failure8%
- Sinus infection6%
- Back pain6%
- Pain in arms and legs6%
- Muscle pain5%
- Sore throat5%
- Upper respiratory infection17%
- Stomach pain7%
- Heart failure
- Liver damage
Current liver problems
- Bladder cancer
History of bladder cancer
- Bone fracture
- Lactic acid build up in blood
History of kidney problems
...and 5 more risk factors
- Low blood sugar
Skipping meals or having inconsistent meal times
...and 4 more risk factors
- Severe allergic reaction
History of allergy to sulfa-containing medicine
- Breakdown of red blood cells
People with G6PD deficiency