Compare Actos vs. glyburide
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.
Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
- Improves sugar control and lowers A1c levels by around 1%.
- Easily taken by mouth as a once a day pill.
- Prevents the harmful effects of high sugar levels on your organs.
- Rarely causes low blood sugar.
- Lower the risk of heart attack or stroke.
- Available as an oral tablet.
- Lowers your A1c (average blood sugar over time) up to 2%.
- Available in generic version.
- Available in single pill combination with other anti-diabetic medicines.
- May take several weeks to lower blood sugar.
- Can cause weight gain.
- People with heart failure or history of bladder cancer shouldn't use this medicine.
- Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
- Raises the risk of bone fractures, especially for people who already have a risk for fractures.
- More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
- You will have to check your blood sugar often when you first start taking it.
- Can cause weight gain (about 2 to 3 pounds).
- Not ideal for elderly or those with poor kidney function.
- May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Have you used Actos (pioglitazone)?Leave a review
- Low blood sugar27%
- Colds and flu13%
- Heart failure8%
- Sinus infection6%
- Back pain6%
- Pain in arms and legs6%
- Muscle pain5%
- Sore throat5%
- Heart failure
- Liver damage
Current liver problems
- Bladder cancer
History of bladder cancer
- Bone fracture
- Low blood sugar
Over age 65
...and 4 more risk factors
- Severe allergic reactions
History of sulfa allergies