Compare Actos vs. Lantus

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Actos (pioglitazone)

Prescription only

Lantus (Insulin Glargine)

Prescription only
Lowers blood sugar.

Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.

4.1/ 7 average rating with 175 reviewsforActos
Lowers blood sugar.

Lantus (Insulin Glargine) is a long-acting insulin that provides all-day sugar control. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.

5.1/ 7 average rating with 584 reviewsforLantus
Upsides
  • Improves sugar control and lowers A1c levels by around 1%.
  • Easily taken by mouth as a once a day pill.
  • Prevents the harmful effects of high sugar levels on your organs.
  • Rarely causes low blood sugar.
  • Lower the risk of heart attack or stroke.
  • Insulin is the most effective blood sugar-lowering medicine. When used correctly, it'll lower blood sugar every time you use it and prevent the harmful effects of high sugar levels on your organs and blood vessels.
  • Lantus is a long-lasting insulin that provides consistent, all-day sugar control with less risk of low blood sugar.
  • Dose can be easily adjusted to make a customized regimen that's tailored to your body.
  • Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression.
  • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
Downsides
  • May take several weeks to lower blood sugar.
  • Can cause weight gain.
  • People with heart failure or history of bladder cancer shouldn't use this medicine.
  • Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
  • Raises the risk of bone fractures, especially for people who already have a risk for fractures.
  • You have to take insulin by injection.
  • You have to check your blood sugar every day.
  • Likely to cause moderate weight gain (around 4 to 6 pounds).
  • Higher risk of low blood sugar episodes than other kinds of diabetes medicines.
Used for
Dosage forms
  • Pill
  • Injection
Price
Lowest price near you
$12.05
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Lowest price near you
$389.68
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Reviews
175 
42%
think this treatment is worth it
30%
think this treatment works well
21%
think this treatment is a hassle

Have you used Actos (pioglitazone)?

Leave a review
584 
67%
think this treatment is worth it
51%
think this treatment works well
14%
think this treatment is a hassle

Have you used Lantus (Insulin Glargine)?

Leave a review
Side effects
10possible side effects
  • Low blood sugar
    27%
  • Swelling
    27%
  • Colds and flu
    13%
  • Headache
    9%
  • Heart failure
    8%
  • Sinus infection
    6%
  • Back pain
    6%
  • Pain in arms and legs
    6%
  • Muscle pain
    5%
  • Sore throat
    5%
See more detailed side effects
2possible side effects
  • Angiopathy
    7%
  • Injection site pain
    3%
See more detailed side effects
Risks and warnings
  • Heart failure

    Heart failure

  • Liver damage

    Current liver problems

  • Bladder cancer

    History of bladder cancer

  • Bone fracture

    Women

See more detailed risks and warnings
  • Life-threatening low blood sugar (Hypoglycemia)

    Insulin dose too high

    ...and 4 more risk factors

  • Complications due to low potassium

    Use of other medicine that lowers potassium

    ...and 1 more risk factors

See more detailed risks and warnings