Compare Actos vs. Victoza

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Actos
(pioglitazone)

Victoza
(liraglutide)

Lowers blood sugar. Actos (Pioglitazone) is a last-choice blood sugar-lowering medicine since it's only moderately effective but has a lot of undesirable side effects.Lowers your blood sugar. Victoza (liraglutide) is a medicine you inject once a day to control diabetes, but it can be expensive.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Actos
Best available price for 30 (30mg) tablets of actos
Coupons for Victoza
Best available price for 9 (3 pens of 18mg/3ml) cartons of victoza
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.11Actos
Reviews for Actos
42%
of people (All ages) say Actos is worth it
30%
say it works well
21%
say it's a big hassle
175 reviews
Have you used Actos (pioglitazone)?
Worth itNot sureNot worth it
Reviews for Victoza
73%
-31% worse vs. Actos
91%
-61% worse vs. Actos
27%
+6% better vs. Actos
Have you used Victoza (liraglutide)?
Worth itNot sureNot worth it
Side effects
ActosVictoza
  • Swelling due to excess fluid 11%
  • Low blood sugar 8%
  • Ear, nose, or throat infection 4%
  • Headache 2%
  • Cardiac failure 2%
  • Back pain 1%
  • Sinus inflammation 1%
  • Muscle pain 2%
More Actos side effects »
  • Nausea 13%
  • Headache 4%
  • Diarrhea 6%
  • Low appetite 9%
  • Runny nose and congestion 1%
  • Head cold 1%
  • Vomiting 4%
  • Constipation 4%
  • Indigestion 3%
  • Back pain 1%
More Victoza side effects »
How it works
ActosVictoza
Actos (Pioglitazone) is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.Victoza (liraglutide) is a medication for diabetes. It stimulates your body to make and release more insulin, stops the body from releasing more sugar, and slows down digestion.
Type of medication
ActosVictoza
Prescription onlyPrescription only
Available as
ActosVictoza
  • Pill
  • Injection
Used for
ActosVictoza
Risk factors for serious side effects
ActosVictoza
  • Heart failure diagnosis
  • Current liver problems
  • Female
Detailed Actos (pioglitazone) risks & warnings »
  • History of MTC
  • History of MEN 2
  • History of pancreatitis
  • History of gallstones
  • alcoholism
Detailed Victoza (liraglutide) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
ActosVictoza
No kidneys and liver related info.
  • Victoza (liraglutide) can cause or worsen kidney damage. This is more likely to happen if you've had nausea or vomiting, diarrhea or dehydration. Make sure to drink plenty of fluids and stay hydrated when you're sick. If you have kidney damage already, your doctor might do regular lab tests while you're taking Victoza (liraglutide) to make sure your kidneys stay healthy.
  • No limitation for people with kidney problems, but close monitoring is recommended.
Weight
ActosVictoza
  • Can cause weight gain, headache, and fluid retention.
  • More likely to cause weight gain (2 to 6 pounds or more) compared to other blood sugar-lowering medicines.
  • Helps with weight loss and controls appetite.
Upsides and benefits
ActosVictoza
  • Oral blood sugar-lowering medicine.
  • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
  • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
  • Rarely causes low blood sugar.
  • Lowers A1c (average blood sugar over time) up to 1.5%.
  • Helps with weight loss and controls appetite.
  • Only medicine in this class with proven heart health benefits.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Medicine is ready to use, without need to mix.
Downsides and risks
ActosVictoza
  • May take several weeks to lower blood sugar.
  • You have to check your blood sugar regularly with this medicine.
  • Has more side effects than similar medicines, so it's usually not the first choice for new Type 2 diabetes patients.
  • More likely to cause weight gain (2 to 6 pounds or more) compared to other blood sugar-lowering medicines.
  • Up to 1 in 10 people might get fluid retention (edema), ranging from mild ankle swelling to severe swelling in the lungs that makes it hard to breathe. People with severe congestive heart failure shouldn't use Actos.
  • Raises the risk of bone fractures, especially for people who already have a risk for fractures.
  • Slightly raises the risk of bladder cancer.
  • Only available as an injection.
  • Brand name medicine and can be expensive.
  • Compared to other similar medicines, you have to inject this every day.
Tips from our pharmacists for people taking the medication
ActosVictoza
  • Takes several weeks to see full effect on blood sugar control.
  • Can cause weight gain, headache, and fluid retention.
  • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
  • Not recommended for patients with certain heart problems.
  • Check your blood sugar regularly.
  • Inject the dose given by your doctor daily at the same time on your belly, thighs, or the back of your upper arm. To be used with or without food.
  • You may have low appetite, nausea, vomiting, diarrhea, or stomach pain, which may get better with time.
  • Let your doctor know if you have severe and/or persistent stomach pain or nausea with or without vomiting.
  • Unused pens should be stored in the refrigerator, but the pen in use can be kept at room temperature for up to 30 days.
Learn more
More about ActosSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Actos (pioglitazone)?
Worth itNot sureNot worth it
More about VictozaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Victoza (liraglutide)?
Worth itNot sureNot worth it