Compare Adderall vs. Intuniv

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Adderall (dextroamphetamine / amphetamine)

Prescription only

Intuniv (guanfacine ER)

Prescription only
Helps you focus and stay alert.

Adderall (dextroamphetamine / amphetamine) is a first-choice treatment for ADHD that's available as a generic, but it's a stimulant that can cause difficulty sleeping and other side effects.

5.3/ 7 average rating with 1309 reviewsforAdderall
Helps you focus your thoughts.

Intuniv (guanfacine ER) is an option for ADHD patients who cannot take stimulants.

Upsides
  • First-choice medication to treat ADHD.
  • Adderall (dextroamphetamine / amphetamine) is used together with counseling or other non-drug therapies to treat ADHD.
  • Available as an affordable generic medication.
  • Available in both immediate and extended release forms.
  • For the extended release capsule, if you can't swallow the whole capsule, the capsule can be opened, mixed in a spoonful of applesauce, and swallowed.
  • Not a stimulant and is an option for people who cannot take stimulants.
  • Can be used either alone or with other stimulant medications.
  • Available in generic.
Downsides
  • Must take in the morning and early afternoon, otherwise it can cause difficulty sleeping.
  • It's a controlled medication and should be locked up to prevent potential abuse.
  • Not safe for people with a history of heart problems.
  • For school-aged children, a second dose will likely need to be given at school.
  • Intuniv (guanfacine ER) can cause changes in your blood pressure so it will be important to watch your blood pressure regularly.
  • May cause drowsiness, dizziness, and headaches especially at higher doses.
  • It can make you feel more irritable or anxious. Talk to your doctor if it bothers you.
  • Not recommended for people over 65 years old.
  • It may cause drowsiness, especially when you first start taking Intuniv (guanfacine ER) or with dose increases, so do not drive until you know how Intuniv (guanfacine ER) affects you.
Used for
Dosage forms
  • Pill
  • Extended release
Price
Lowest price near you
$226.95
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Lowest price near you
$28.78
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Reviews
1309 
74%
think this treatment is worth it
53%
think this treatment works well
16%
think this treatment is a hassle

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Side effects
The Adderall (dextroamphetamine / amphetamine) FDA package insert doesn’t have numbers about how common side effects are.
10possible side effects
  • Headache
    27%
  • Fatigue
    22%
  • Dizziness
    16%
  • Loss of appetite
    15%
  • Stomach pain
    12%
  • Irritability
    7%
  • Anxiety
    5%
  • Rash
    3%
  • Constipation
    3%
  • Weight gain
    3%
See more detailed side effects
Risks and warnings
  • Serious or life-threatening cardiovascular events

    History of heart problems

    ...and 1 more risk factors

  • Dependence and abuse

    History of drug abuse

    ...and 1 more risk factors

  • Serotonin syndrome

    Taking other medicines that affect serotonin levels

  • Aggressive behavior and psychosis

    History of psychotic episodes

    ...and 1 more risk factors

  • Driving impairment

    Taking Adderall (dextroamphetamine / amphetamine) with alcohol

    ...and 1 more risk factors

  • Long-term growth suppression

    Children ages 7 to 10

See more detailed risks and warnings
  • Fainting

    High blood pressure

    ...and 1 more risk factors

  • Increased blood pressure and heart rate

    Stopping Intuniv (guanfacine ER) suddenly.

  • Heart problems

    History of heart problem

See more detailed risks and warnings