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Advair Diskus
(Fluticasone / Salmeterol)

Prevents breathing problems. Advair Diskus (Fluticasone / Salmeterol) is good for people who need two medicines to control their asthma or COPD, but it might be expensive since there's no generic available.
How it works
Advair Diskus (Fluticasone / Salmeterol) is a combination medicine. Fluticasone (a corticosteroid) lowers lung inflammation to control asthma and COPD. Salmeterol (a bronchodilator) relaxes muscles in your lungs to open airways and make breathing easier.
Type of medication
Long-acting bronchodilator
Prescription only
Available as
  • Inhaler
Used for (click to learn more)
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Reviews & ratings
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Reviews for Advair Diskus (Fluticasone / Salmeterol)
of people say Advair Diskus (Fluticasone / Salmeterol) is worth it
say it works well
say it's a big hassle
Side effects
  • Ear, nose, or throat infection 13%
  • Candidiasis mouth/throat 9%
  • Lung infection 8%
  • Sore throat 7%
  • Bronchitis 6%
  • Nausea and vomiting 5%
  • Headaches 4%
  • Cough 4%
  • Diarrhea 3%
  • Viral respiratory infections 3%
More Advair side effects »
Risk factors for serious side effects
  • Adverse effect of long-acting beta agonist drugs (LABAs), one of the medications in Advair Diskus (Fluticasone / Salmeterol), a combination drug.
  • History of chronic obstructive pulmonary disease (COPD)
  • COPD includes chronic bronchitis and emphysema
  • Age greater than 65 years
  • Lowering dose or stopping Advair Diskus (Fluticasone / Salmeterol) too quickly especially after long-term treatment
  • Stress such as trauma, surgery or infection
  • Not rinsing mouth after use
  • Higher dose of the corticosteroid medication contained in Advair Diskus (Fluticasone / Salmeterol)
  • Adverse effect of long-acting beta agonist drugs (LABAs), one of the medications in Advair Diskus (Fluticasone / Salmeterol), a combination drug.
  • History of arrhythmia, hypertension or heart failure
  • Severe milk protein allergy
Detailed Advair Diskus (Fluticasone / Salmeterol) risks & warnings »
Pregnancy category
No specific alcohol-related info.
No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.
No specific sex-related info.
  • Advair Diskus (Fluticasone / Salmeterol) may increase blood pressure and heart rate, especially if you already have these conditions. These symptoms are related to one of the medications in this product so don't change or increase your dose without talking to your doctor first. Tell your doctor if you develop dizziness, tremor, nausea, rapid heartbeat, become very tired or have difficulty sleeping while taking Advair Diskus (Fluticasone / Salmeterol), you may need to change or stop this medication.
No specific weight-related info.
Upsides and benefits
  • 2-in-1 medicine that lowers inflammation and opens airways in your lungs. Medicines are more effective together than alone.
  • Makes lung function significantly better.
  • Lowers the number of flare-ups and rescue inhaler uses in asthma and COPD.
  • You only have to use it twice a day.
  • Both the Diskus and inhaler can be used to treat asthma.
Downsides and risks
  • You have to use Advair every day to control your symptoms.
  • You can't lower the dose or stop taking it too suddenly.
  • The HFA inhaler isn't approved to treat COPD.
  • Can make your heart race.
  • Steroids can slow height growth in kids.
  • Because steroids suppress your immune system, you can catch bacterial and viral infections easier, and they can take longer to go away.
  • There have been some reports of worsening asthma leading to death when taking this medicine.
Tips from our pharmacists for people taking the medication
  • Lowers inflammation and opens airways to improve breathing.
  • Starts working in about 30 minutes, but it can take 1 to 2 weeks to feel the full effects.
  • Prevents asthma symptoms, but doesn't treat sudden wheezing or asthma attacks once they start.
  • Use inhaler in a level position, and don't breathe out into the device.
  • Rinse your mouth out with water after each use.
  • Shake inhaler for 5 seconds before you use it.
  • Pump the inhaler 4 times before inhaling the first dose, or if it's been more than a month since your last dose.
  • Call 911 or your doctor if it's hard to breathe or you have an asthma attack while on this medication.
  • Diskus contains lactose, so don't use it if you're allergic to milk protein.
Learn more
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