Compare Advair vs. Combivent

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prevents breathing problems.

Advair (fluticasone / salmeterol) combines two medicines into one inhaler, but it might be expensive.

3.8/ 5 average rating with 799 reviewsforAdvair
Makes it easier to breathe.

Combivent (Ipratropium / Albuterol) is good for people who need 2 medicines to relieve their COPD symptoms, but you need to be okay with taking it four times a day.

3.4/ 5 average rating with 142 reviewsforCombivent
Upsides
  • 2-in-1 medicine is more effective together than alone.
  • The diskus is used to treat both COPD and asthma.
  • 2-in-1 medicine that opens airways and makes it easier to breathe. Medicines are more effective together than alone.
  • Effectively relieves COPD and asthma symptoms.
  • Respimat formulation has a clear display for dosing, doesn't require shaking, and only needs one inhalation per dose.
Downsides
  • Take it daily and consistently for the best results. It is not for on-demand treatment of wheezing or asthma attacks.
  • Rinse your mouth with water after each inhalation to avoid fungal infections of the mouth.
  • You have to use Combivent four times a day.
  • Can make your heart race.
  • Can make symptoms of enlarged prostate or urinary blockage worse.
  • Can worsen a certain type of glaucoma.
Used for
Dosage forms
  • Inhaler
  • Inhaler
Price
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Reviews
799 reviews so far
66%
saidit'sworth it
48%
saiditworked well
11%
saidit'sa big hassle

Have you used Advair (fluticasone / salmeterol)?

Leave a review
142 reviews so far
63%
saidit'sworth it
37%
saiditworked well
13%
saidit'sa big hassle

Have you used Combivent (Ipratropium / Albuterol)?

Leave a review
Side effects
15possible side effects
  • Lung infection
    27%
  • Sore throat
    13%
  • Headaches
    12%
  • Lung inflammation
    7%
  • Hoarseness
    5%
  • Sinus inflammation
    4%
  • Colds and flu
    4%
  • Nausea and vomiting
    4%
  • Stomach upset
    4%
  • Diarrhea
    4%
  • Muscle and joint pain
    4%
  • Stomach flu
    3%
  • Fungal infections
    3%
  • Cough
    3%
  • Bronchitis
    2%
See more detailed side effects
10possible side effects
  • Bronchitis
    12%
  • Upper Respiratory Tract Infection
    11%
  • Headache
    6%
  • Dyspnea
    5%
  • Coughing
    4%
  • Pain
    3%
  • Respiratory Disorders
    3%
  • Nausea
    2%
  • Pharyngitis
    2%
  • Sinusitis
    2%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Asthma
    • Children under 18
  • Increased risk of infections
    • History of chronic obstructive pulmonary disease (COPD)
    • COPD includes chronic bronchitis and emphysema
    • Age greater than 65 years
  • Mouth and throat infection
    • Not rinsing mouth after use
    • Higher dose of the corticosteroid medication contained in Advair (fluticasone / salmeterol)
  • Asthma attack
  • Heart disease
    • High blood pressure
    • Heart failure
    • Heart beat problems
    • Taking more Advair (fluticasone / salmeterol) than recommended
  • Serious allergic reaction
    • Milk allergy
See more detailed risks and warnings
  • Sudden onset difficulty breathing (paradoxical bronchospasm)
  • Heart disease
    • History of rapid heartbeat
    • History of high blood pressure
    • history of heart failure or chest pain.
  • Worsening glaucoma
    • History of narrow-angle glaucoma
    • History of high eye pressure
  • Eye problems
    • Spraying Combivent (Ipratropium / Albuterol) into eyes
  • Difficulty urinating
    • History of urinary bladder blockage (urinary obstruction)
    • History of enlarged prostate
  • Serious allergic reaction
    • History of atropine allergic reaction
  • Low potassium
    • Taking Combivent (Ipratropium / Albuterol) with drugs that decrease potassium
    • History of low potassium
  • Food allergies
    • Taking Combivent (Ipratropium / Albuterol) aerosol inhaler
    • History of soybean allergy
    • History of peanut allergy
See more detailed risks and warnings