Compare Advair vs. Cromolyn

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advair Diskus
(fluticasone / salmeterol)


Prevents breathing problems. Advair Diskus (Fluticasone / Salmeterol) is good for people who need two medicines to control their asthma or COPD, but it might be expensive since there's no generic available.Relieves nasal allergy symptoms. Intal (Cromolyn) is a good option to relieve nasal allergy symptoms when antihistamines aren't working. Good choice for pregnant women.
Reviews & ratings
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Reviews for Advair
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say it works well
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799 reviews
Have you used Advair Diskus (fluticasone / salmeterol)?
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Have you used Intal (cromolyn)?
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Side effects
  • Lung infection 6%
  • Headaches 4%
  • Candidiasis mouth/throat 9%
  • Throat irritation 1%
  • Viral respiratory infections 3%
  • Hoarseness/dysphonia 5%
  • Dizziness 2%
  • Fever 1%
More Advair side effects »

We haven’t found good data for Cromolyn side effects.

FDA side effect reports for Cromolyn »
How it works
Advair Diskus (Fluticasone / Salmeterol) is a combination medicine. Fluticasone (a corticosteroid) lowers lung inflammation to control asthma and COPD. Salmeterol (a bronchodilator) relaxes muscles in your lungs to open airways and make breathing easier.Intal (Cromolyn) is a mast-cell stabilizer nasal spray that prevents and treats seasonal allergies.
Type of medication
Prescription onlyPrescription or OTC
Available as
  • Inhaler
  • Nasal spray
Used for
Risk factors for serious side effects
  • Adverse effect of long-acting beta agonist drugs (LABAs), one of the medications in Advair Diskus (Fluticasone / Salmeterol), a combination drug.
  • History of chronic obstructive pulmonary disease (COPD)
  • COPD includes chronic bronchitis and emphysema
  • Age greater than 65 years
  • Lowering dose or stopping Advair Diskus (Fluticasone / Salmeterol) too quickly especially after long-term treatment
Detailed Advair Diskus (fluticasone / salmeterol) risks & warnings »
    Coming soon.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Kidneys and liver
    • Adrenal suppression can occur if you lower your dose or stop taking Advair Diskus (Fluticasone / Salmeterol) too quickly which is related to one of the medications in the combination. Symptoms include joint or muscle pain, extreme low energy and depression. Changes in your medication need to be done slowly and over time. Talk to your doctor before you decrease or stop Advair Diskus (Fluticasone / Salmeterol).
    No kidneys and liver related info.
    No sleep related info.
    • Doesn't make you drowsy or dizzy.
    • Steroids can slow height growth in kids.
    No weight related info.
    Upsides and benefits
    • 2-in-1 medicine that lowers inflammation and opens airways in your lungs. Medicines are more effective together than alone.
    • Makes lung function significantly better.
    • Lowers the number of flare-ups and rescue inhaler uses in asthma and COPD.
    • You only have to use it twice a day.
    • Both the Diskus and inhaler can be used to treat asthma.
    • Treats nasal allergy symptoms.
    • Most people don't have many side effects since it works in the nose and doesn't affect the rest of your body.
    • It's a good option for pregnant women. Can also be used for kids 2 years and older.
    • Doesn't make you drowsy or dizzy.
    • No prescription is needed.
    Downsides and risks
    • You have to use Advair every day to control your symptoms.
    • You can't lower the dose or stop taking it too suddenly.
    • The HFA inhaler isn't approved to treat COPD.
    • Can make your heart race.
    • Steroids can slow height growth in kids.
    • Because steroids suppress your immune system, you can catch bacterial and viral infections easier, and they can take longer to go away.
    • There have been some reports of worsening asthma leading to death when taking this medicine.
    • Needs to be used regularly for at least a week to see any good effects.
    • Can have an unpleasant smell or taste.
    • Can cause headaches, or burning and stinging in your nose.
    Tips from our pharmacists for people taking the medication
    • Lowers inflammation and opens airways to improve breathing.
    • Starts working in about 30 minutes, but it can take 1 to 2 weeks to feel the full effects.
    • Prevents asthma symptoms, but doesn't treat sudden wheezing or asthma attacks once they start.
    • Use inhaler in a level position, and don't breathe out into the device.
    • Rinse your mouth out with water after each use.
    • Shake inhaler for 5 seconds before you use it.
    • Pump the inhaler 4 times before inhaling the first dose, or if it's been more than a month since your last dose.
    • Call 911 or your doctor if it's hard to breathe or you have an asthma attack while on this medication.
    • Diskus contains lactose, so don't use it if you're allergic to milk protein.
    • Works best when used one week before exposure to allergens. It takes about 1 to 2 weeks until you feel the full effects.
    • Check with your doctor or pharmacist to make sure you know how to use this nose spray. Don't use more than recommended.
    • Shake the spray gently and clear your nose before each use.
    • Before using it for the first time, prime the spray pump until you see a fine mist.
    • Breathe in slowly as you're spraying. Wait a few minutes before blowing your nose if needed.
    Learn more
    More about AdvairSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Advair Diskus (fluticasone / salmeterol)?
    Worth itNot sureNot worth it
    More about CromolynSide effectsAlternativesFDA package insert
    Have you used Intal (cromolyn)?
    Worth itNot sureNot worth it