Compare Advair vs. Singulair

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advair (fluticasone / salmeterol)

Prescription only

Singulair (Montelukast)

Prescription only
Prevents breathing problems.

Advair (fluticasone / salmeterol) combines two medicines into one inhaler, but it might be expensive.

5.2/ 7 average rating with 799 reviewsforAdvair
Prevents breathing problems.

Singulair (Montelukast) has fewer side effects but doesn't work as well as steroid inhalers for asthma. It also helps with allergies.

5.1/ 7 average rating with 557 reviewsforSingulair
Upsides
  • 2-in-1 medicine is more effective together than alone.
  • The diskus is used to treat both COPD and asthma.
  • Prevents symptoms and improves lung function in children and adults with chronic asthma.
  • A single 10 mg dose improves exercise-induced asthma symptoms for up to 24 hours.
  • Fewer side effects compared to other asthma treatments.
  • Also relieves nasal allergy symptoms.
  • Effective pill alternative to corticosteroid inhalers.
Downsides
  • Take it daily and consistently for the best results. It is not for on-demand treatment of wheezing or asthma attacks.
  • Rinse your mouth with water after each inhalation to avoid fungal infections of the mouth.
  • You have to use Montelukast every day to control your symptoms.
  • Somewhat less effective than corticosteroid inhalers for asthma.
  • There's no generic available, so it can be expensive.
  • Can cause behavior changes, agitation, aggression, and difficulty sleeping for some people.
Used for
Dosage forms
  • Inhaler
  • Pill
  • Chewable tablet
  • Granule
Price
Lowest price near you
$48.58
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Lowest price near you
$10.25
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Reviews
799 
66%
think this treatment is worth it
48%
think this treatment works well
11%
think this treatment is a hassle

Have you used Advair (fluticasone / salmeterol)?

Leave a review
557 
66%
think this treatment is worth it
47%
think this treatment works well
14%
think this treatment is a hassle

Have you used Singulair (Montelukast)?

Leave a review
Side effects
10possible side effects
  • Lung infection
    27%
  • Sore throat
    13%
  • Headaches
    12%
  • Lung inflammation
    7%
  • Hoarseness
    5%
  • Sinus inflammation
    4%
  • Colds and flu
    4%
  • Nausea and vomiting
    4%
  • Stomach upset
    4%
  • Diarrhea
    4%
See more detailed side effects
10possible side effects
  • Headache
    18%
  • Influenza
    4%
  • Pain, abdominal
    3%
  • Cough
    3%
  • Asthenia/fatigue
    2%
  • Fever
    2%
  • Dyspepsia
    2%
  • Pain, dental
    2%
  • Gastroenteritis, infectious
    2%
  • Dizziness
    2%
See more detailed side effects
Risks and warnings
  • Increased risk of death

    Asthma

    ...and 1 more risk factors

  • Increased risk of infections

    History of chronic obstructive pulmonary disease (COPD)

    ...and 2 more risk factors

  • Mouth and throat infection

    Not rinsing mouth after use

    ...and 1 more risk factors

  • Heart disease

    High blood pressure

    ...and 3 more risk factors

  • Serious allergic reaction

    Milk allergy

See more detailed risks and warnings
  • Sudden onset of asthma

    Exercise-induced asthma

    ...and 1 more risk factors

  • Blood disorder (eosinophilia)

    Recent treatment with corticosteroid medication

    ...and 1 more risk factors

  • Brain damage from too much phenylalanine

    History of phenylketonuria (PKU)

  • Liver damage

    History of liver disease including hepatitis

    ...and 2 more risk factors

See more detailed risks and warnings