Compare Advair vs. Spiriva

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prevents breathing problems.

Advair (fluticasone / salmeterol) combines two medicines into one inhaler, but it might be expensive.

3.8/ 5 average rating with 799 reviewsforAdvair
Makes it easier to breathe.

Spiriva (Tiotropium) works well to reduce COPD symptoms and flare-ups with fewer side effects than some medicines that open airways, but you have to use it every day.

3.5/ 5 average rating with 74 reviewsforSpiriva
Upsides
  • 2-in-1 medicine is more effective together than alone.
  • The diskus is used to treat both COPD and asthma.
  • Helps you breathe easier and lessens the need for a fast-acting (rescue) inhaler.
  • Reduces flare-ups and hospitalizations with fewer side effects compared to some other medicines that open airways.
  • You only need to take it once a day.
Downsides
  • Take it daily and consistently for the best results. It is not for on-demand treatment of wheezing or asthma attacks.
  • Rinse your mouth with water after each inhalation to avoid fungal infections of the mouth.
  • Won't cure your COPD (but it will relieve your symptoms).
  • You'll need to use this medicine for a long time, and you have to take it every day.
  • Can make symptoms of enlarged prostate or urinary blockage worse.
  • Can worsen a certain type of glaucoma.
  • You might feel dizzy or have blurry vision while taking this medicine.
Used for
Dosage forms
  • Inhaler
  • Inhaler
Price
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Reviews
799 reviews so far
66%
saidit'sworth it
48%
saiditworked well
11%
saidit'sa big hassle

Have you used Advair (fluticasone / salmeterol)?

Leave a review
74 reviews so far
64%
saidit'sworth it
46%
saiditworked well
8%
saidit'sa big hassle

Have you used Spiriva (Tiotropium)?

Leave a review
Side effects
15possible side effects
  • Lung infection
    27%
  • Sore throat
    13%
  • Headaches
    12%
  • Lung inflammation
    7%
  • Hoarseness
    5%
  • Sinus inflammation
    4%
  • Colds and flu
    4%
  • Nausea and vomiting
    4%
  • Stomach upset
    4%
  • Diarrhea
    4%
  • Muscle and joint pain
    4%
  • Stomach flu
    3%
  • Fungal infections
    3%
  • Cough
    3%
  • Bronchitis
    2%
See more detailed side effects
36possible side effects
  • Respiratory tract Infection
    41%
  • Dry mouth
    16%
  • Pharyngitis
    13%
  • Sinusitis
    11%
  • Chest pain (non-specific)
    7%
  • Urinary tract Infection
    7%
  • Dyspepsia
    6%
  • Rhinitis
    6%
  • Headache
    6%
  • Edema, Dependent
    5%
  • Abdominal pain
    5%
  • Constipation
    5%
  • Dry Mouth
    5%
  • Vomiting
    4%
  • Myalgia
    4%
  • Infection
    4%
  • Moniliasis
    4%
  • Epistaxis
    4%
  • Rash
    4%
  • Depression
    4%
  • Insomnia
    4%
  • Arthralgia
    4%
  • Allergic reaction
    3%
  • Leg pain
    3%
  • Dysphonia
    3%
  • Parathesia
    3%
  • Gastroinestinal disorder not otherwise specified
    3%
  • Castroesophegeal reflux
    3%
  • Stomatitis
    3%
  • Hypercholesterolemia
    3%
  • Hyperglycemia
    3%
  • Skeletal pain
    3%
  • Angina pectoris
    3%
  • Herpes zoster
    3%
  • Laryngitis
    3%
  • Cataract
    3%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Asthma
    • Children under 18
  • Increased risk of infections
    • History of chronic obstructive pulmonary disease (COPD)
    • COPD includes chronic bronchitis and emphysema
    • Age greater than 65 years
  • Mouth and throat infection
    • Not rinsing mouth after use
    • Higher dose of the corticosteroid medication contained in Advair (fluticasone / salmeterol)
  • Asthma attack
  • Heart disease
    • High blood pressure
    • Heart failure
    • Heart beat problems
    • Taking more Advair (fluticasone / salmeterol) than recommended
  • Serious allergic reaction
    • Milk allergy
See more detailed risks and warnings
  • Serious allergic reaction
    • History of atropine allergic reaction
  • Sudden onset difficulty breathing (paradoxical bronchospasm)
  • Worsening glaucoma
    • History of narrow-angle glaucoma
  • Difficulty urinating
    • History of urinary bladder blockage (urinary obstruction)
    • History of enlarged prostate
  • Serious allergic reaction
    • Severe milk protein allergy
  • Reduced kidney function
    • History of moderate to severe kidney disease
  • Feeling dizzy
    • Taking with other anticholinergic medications
See more detailed risks and warnings