Compare Advil Allergy and Congestion Relief vs. Advil Cold and Sinus

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advil Allergy And Congestion Relief
(Chlorpheniramine / Ibuprofen / Phenylephrine)

Advil Cold And Sinus
(Ibuprofen / Pseudoephedrine)

Relieves cold and allergy symptoms. Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is an okay combination medicine to relieve pain and congestion. The antihistamine can make you sleepy and the decongestant can keep you awake, so it could affect you either way.Relieves sinus pain and congestion. Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.913709116214336Advil Allergy and Congestion Relief
Reviews for Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)
73%
of people say Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is worth it
30%
say it works well
6%
say it's a big hassle
Reviews for Advil Cold And Sinus (Ibuprofen / Pseudoephedrine)
75%
+2% vs. Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)
34%
+4% vs. Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)
6%
Same vs. Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)
Side effects
Advil Allergy and Congestion ReliefAdvil Cold and Sinus

We haven’t found good data for Advil Allergy and Congestion Relief side effects.

FDA side effect reports for Advil Allergy and Congestion Relief »

We haven’t found good data for Advil Cold and Sinus side effects.

FDA side effect reports for Advil Cold and Sinus »
How it works
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is a combination medicine that treats cold and allergy symptoms. Ibuprofen is an NSAID that relieves swelling, pain, and fever. Chlorpheniramine is an antihistamine that treats runny nose and watery eyes. Phenylephrine is a decongestant that clears your sinuses.Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) is a combination medicine that relieves cold symptoms and sinus pressure. Ibuprofen (an NSAID) relieves pain and reduces fever. Pseudoephedrine (a decongestant) clears your sinuses.
Type of medication
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
Antihistamine
1st generation
Pain reliever
NSAID
DecongestantOver-the-counter
Pain reliever
NSAID
DecongestantOver-the-counter
Available as
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
  • Pill
  • Pill
Used for (click to learn more)
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
Risk factors for serious side effects
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Women of childbearing age
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • History of high blood pressure
  • History of heart problems
  • Age 65 years or older
  • Taking with aspirin
Detailed Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) risks & warnings »
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Women of childbearing age
  • History of high blood pressure
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • History of heart problems
  • Age 65 years or older
  • Taking with aspirin
Detailed Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) risks & warnings »
Pregnancy category
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
  • While taking this, avoid alcohol and other drugs that make you drowsy.
No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
  • Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) contains ibuprofen, an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) for any amount of time.
  • Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) contains ibuprofen, an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) for any amount of time.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
  • While taking this, avoid alcohol and other drugs that make you drowsy.
No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
  • Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) is a combination medicine that relieves cold symptoms. It's good to use if you have congestion, sore throat, headache, or fever.
  • Ibuprofen (a pain reliever) is more effective than acetaminophen at lowering fever and relieving sinus pain.
  • Pseudoephedrine (a decongestant) clears nose congestion to help you breathe better.
Downsides and risks
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
  • If you don't need both of the medications in this combination, you'd be taking extra medicine and can have extra side effects for no reason.
  • Pseudoephedrine, the decongestant in Advil Cold And Sinus (Ibuprofen / Pseudoephedrine), can make your heart race or make you feel anxious and restless.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
Tips from our pharmacists for people taking the medication
Advil Allergy and Congestion ReliefAdvil Cold and Sinus
  • Chlorpheniramine (the antihistamine ingredient in Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)) can make you sleepy, so avoid activities that require you to be fully alert until you know how it affects you.
  • While taking this, avoid alcohol and other drugs that make you drowsy.
  • Phenylephrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Let your doctor know if your symptoms don't improve in a few days.
  • Don't use in kids age 12 years or younger.
  • Don't take it if you have an allergy to aspirin since ibuprofen can cause a similar reaction.
  • Starts working in 30 minutes.
  • You need to show an ID to buy Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
  • Take it after eating to avoid getting an upset stomach.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • Be careful taking Advil Cold And Sinus (Ibuprofen / Pseudoephedrine) if you have a history of bleeding problems or ulcers since it can make them worse.
  • Talk to your doctor if symptoms don't get better in 1 week.
  • Don't take it if you have an allergy to aspirin since ibuprofen can cause a similar reaction.
Learn more
More about Advil Allergy and Congestion ReliefSide effectsReviews & ratingsAlternativesFDA package insert
More about Advil Cold and SinusSide effectsReviews & ratingsAlternativesFDA package insert