Compare Advil Congestion Relief vs. Allegra-D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relieves pain and congestion.

Advil Congestion Relief (Ibuprofen / Phenylephrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.

3.6/ 5 average rating with 1125 reviewsforAdvil Congestion Relief
Treats allergy symptoms and congestion.

Allegra-D (fexofenadine / pseudoephedrine) is a combination allergy medicine that's useful if you have congestion and runny nose.

Upsides
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Allegra-D (fexofenadine / pseudoephedrine) contains two medicines that work in different ways to help relieve multiple symptoms including nasal congestion and allergies.
  • Available without a prescription in the drugstore.
Downsides
  • If you don't really need both of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
  • You must show a photo ID to purchase this medicine from behind the pharmacy counter. There's a maximum limit on how much Allegra-D (fexofenadine / pseudoephedrine) you can buy at a time.
  • Allegra-D (fexofenadine / pseudoephedrine) can have more side effects (such as increased blood pressure and difficulty sleeping) than Allegra since it has pseudoephedrine in it.
  • If you have severe high blood pressure or heart disease you can't take this medicine. If you have kidney damage, you may not be able to take Allegra-D (fexofenadine / pseudoephedrine).
Used for
Dosage forms
  • Pill
  • Pill
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No pricing information available
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Reviews
1125 reviews so far
73%
saidit'sworth it
32%
saiditworked well
7%
saidit'sa big hassle

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Side effects
The Advil Congestion Relief (Ibuprofen / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
10possible side effects
  • Headache
    13%
  • Trouble sleeping
    13%
  • Nausea
    7%
  • Dry Mouth
    3%
  • Indigestion
    3%
  • Throat irritation
    2%
  • Dizziness
    2%
  • Agitation
    2%
  • Back pain
    2%
  • Palpitations
    2%
See more detailed side effects
Risks and risk factors
  • Stomach bleeding
    • History of stomach bleeding or ulcers
    • Age 60 years or older
    • Taking aspirin, NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day
  • Harm to fetus
    • Women of childbearing age
  • High blood pressure
    • History of high blood pressure
  • Lower kidney function
    • Kidney disease
    • Heart failure
    • Liver disease
    • Taking high blood pressure medications
    • Age 65 years or older
  • Heart attack or stroke
    • History of heart problems
    • Age 65 years or older
    • Taking with aspirin
See more detailed risks and warnings
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • High blood pressure
    • History of high blood pressure
  • Heart problems
    • History of heart problems
    • Age 65 or older
  • Seizure
    • History of seizure
See more detailed risks and warnings