Compare Advil Congestion Relief vs. Allegra D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advil Congestion Relief
(Ibuprofen / Phenylephrine)

Allegra D
(Pseudoephedrine / Fexofenadine)

Relieves pain and congestion. Advil Congestion Relief (Ibuprofen / Phenylephrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.Treats allergy symptoms and congestion. Allegra D (Pseudoephedrine / Fexofenadine) is a combination allergy medicine that's useful if you have congestion and runny nose.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.9Advil Congestion Relief
Reviews for Advil Congestion Relief (Ibuprofen / Phenylephrine)
73%
of people (All ages) say Advil Congestion Relief (Ibuprofen / Phenylephrine) is worth it
32%
say it works well
7%
say it's a big hassle
1125 reviews
Have you used Advil Congestion Relief (Ibuprofen / Phenylephrine)?
Worth itNot sureNot worth it

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Have you used Allegra D (Pseudoephedrine / Fexofenadine)?
Worth itNot sureNot worth it
Side effects
Advil Congestion ReliefAllegra D

We haven’t found good data for Advil Congestion Relief side effects.

FDA side effect reports for Advil Congestion Relief »
  • Headache 3%
  • Back pain 2%
  • Sleep difficulty 13%
  • Nausea 7%
  • Adverse effects 4%
  • Indigestion 3%
  • Dry mouth 3%
  • Dizziness 2%
  • Agitation 2%
More Allegra D side effects »
How it works
Advil Congestion ReliefAllegra D
Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that treats cold and allergy symptoms. Ibuprofen is an NSAID that relieves swelling, pain, and fever. Phenylephrine is a decongestant that clears your sinuses.Allegra D (Pseudoephedrine / Fexofenadine) is a combination medicine that relieves allergy symptoms. Fexofenadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itching. Pseudoephedrine (a decongestant) clears your sinuses.
Type of medication
Advil Congestion ReliefAllegra D
Over-the-counter
Prescription or OTC
Available as
Advil Congestion ReliefAllegra D
  • Pill
  • Extended release
Used for
Advil Congestion ReliefAllegra D
Risk factors for serious side effects
Advil Congestion ReliefAllegra D
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Women of childbearing age
  • History of high blood pressure
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • History of heart problems
  • Age 65 years or older
  • Taking with aspirin
Detailed Advil Congestion Relief (Ibuprofen / Phenylephrine) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • History of high blood pressure
  • History of heart problems
  • Age 65 or older
  • History of seizure
  • Women of childbearing age
Detailed Allegra D (Pseudoephedrine / Fexofenadine) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
Advil Congestion ReliefAllegra D
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
No interactions related info.
Kidneys and liver
Advil Congestion ReliefAllegra D
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) contains ibuprofen, an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil Congestion Relief (Ibuprofen / Phenylephrine) for any amount of time.
No kidneys and liver related info.
Pain
Advil Congestion ReliefAllegra D
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
No pain related info.
Sleep
Advil Congestion ReliefAllegra D
No sleep related info.
  • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
Upsides and benefits
Advil Congestion ReliefAllegra D
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Available without a prescription in the drugstore.
  • It has two medications that work in different ways to help relieve nasal symptoms.
  • The antihistamine (fexofenadine) is useful for relieving itchy eyes, runny nose, or constant sneezing.
  • The decongestant (pseudoephedrine) is very good at relieving congestion.
Downsides and risks
Advil Congestion ReliefAllegra D
  • If you don't really need both of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
  • Has more side effects than Allegra since it has pseudoephedrine in it.
  • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • The decongestant (pseudoephedrine) can make your blood pressure higher and can make it harder to sleep.
  • You must show a photo ID to buy this from behind the pharmacy counter. There's a maximum limit on how much you can buy in the pharmacy at a time.
Tips from our pharmacists for people taking the medication
Advil Congestion ReliefAllegra D
  • Starts working in 30 minutes.
  • Don't take it if you have an allergy to aspirin since ibuprofen can cause a similar reaction.
  • Phenylephrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Follow age-specific dosing instructions on how much to take. Don't take more than what's recommended on the package.
  • Let your doctor know if your symptoms don't improve in a few days.
  • It works best if you have nasal congestion and a runny nose.
  • Take on an empty stomach, 1 hour before eating or 2 hours after eating.
  • Shouldn't be used in kids younger than 12 years old.
  • Avoid taking it close to bedtime to prevent trouble sleeping.
  • Can cause dizziness, headache, or a fast heartbeat.
  • Talk to your doctor if you have high blood pressure or kidney problems before using it.
  • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
Learn more
More about Advil Congestion ReliefSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Advil Congestion Relief (Ibuprofen / Phenylephrine)?
Worth itNot sureNot worth it
More about Allegra DSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Allegra D (Pseudoephedrine / Fexofenadine)?
Worth itNot sureNot worth it