Compare Aggrenox vs. Coumadin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prevents blood clots that can cause a stroke.

Aggrenox (Aspirin / Dipyridamole) prevents blood clots and stroke, but cheaper options are available that work just as well.

Prevents blood clots.

Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.

3.8/ 5 average rating with 513 reviewsforCoumadin
Upsides
  • This helps to prevent strokes for people who had a stroke or TIA (transient ischemic attack) before.
  • In clinical studies, Aggrenox (Aspirin / Dipyridamole) lowered the chance of another stroke for a person with a previous stroke or mini-stroke (TIA) by 36%.
  • Works better than either aspirin or dipyridamole alone to prevent strokes.
  • Works as well as Plavix (clopidogrel), another antiplatelet medication, to prevent stroke.
  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
Downsides
  • Raises your risk for bleeding and bruising.
  • Has to be taken twice a day unlike Plavix that only has to be taken once daily.
  • Can be more expensive than other alternatives that are available as a generic.
  • Can't be used by people with an aspirin allergy, or a history of stomach ulcers.
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
Used for
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Reviews
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513 reviews so far
61%
saidit'sworth it
54%
saiditworked well
21%
saidit'sa big hassle

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Side effects
27possible side effects
  • Headache
    40%
  • Dyspepsia
    20%
  • Abdominal Pain
    20%
  • Nausea
    20%
  • Diarrhea
    13%
  • Vomiting
    8%
  • Pain
    6%
  • Fatigue
    6%
  • Arthralgia
    6%
  • Back Pain
    5%
  • Dizziness
    5%
  • Accidental Injury
    3%
  • Hemorrhage NOS
    3%
  • Convulsions
    2%
  • Hemorrhage Rectum
    2%
  • Melena
    2%
  • Malaise
    2%
  • Asthenia
    2%
  • Amnesia
    2%
  • Arthritis
    2%
  • Coughing
    2%
  • Cardiac Failure
    2%
  • Epistaxis
    2%
  • Neoplasm NOS
    2%
  • Anemia
    2%
  • Stroke
    2%
  • Transient Ischemic Attack
    2%
See more detailed side effects
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Brain damage or death from Reyes Syndrome
    • Children 18 years or younger recovering from viral infections
  • Stomach bleeding
    • History of stomach bleeding or ulcers
    • Age 60 or older
    • Also taking other blood thinners
    • Drinking 3 or more alcoholic drinks a day
  • Serious allergic reactions
    • Asthma
    • Rhinitis
    • Nasal Polyps
    • Aspirin Allergy
    • NSAID Allergy
  • Harm to unborn babies
  • Bruising or bleeding
    • Hemophilia
    • von Willebrand's disease
    • low blood platelet count
    • Also taking other blood thinners
    • History of stroke or TIA
    • Liver disease
  • Worsening heart disease
    • Coronary artery disease
    • Angina
    • Prior heart attack
  • Taking the wrong aspirin dose for heart protection
    • Coronary artery disease
    • Angina
    • History of heart attack
    • History of heart bypass surgery
    • History of coronary artery stent placement
  • Liver damage
  • Low blood pressure
    • Prior episodes of low blood pressure
    • Taking blood pressure medications
  • Kidney damage
    • Severe kidney disease
See more detailed risks and warnings
  • Life threatening bleeding
    • Coumadin (warfarin) dose too high
    • Age greater than 65 year
    • History of stomach bleeding
    • High blood pressure
    • Kidney or liver problems
    • Drug interactions
    • Change in lifestyle or diet
    • Alcohol use
    • Certain genetic factors
  • Harm to fetus
    • Women of childbearing age
  • Drug and diet interactions
  • Potential surgery or amputation
See more detailed risks and warnings