Compare Aggrenox vs. Heparin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

(Aspirin / Dipyridamole)


Prevents blood clots that can cause a stroke. Aggrenox (Aspirin / Dipyridamole) prevents blood clots and stroke, but cheaper options are available that work just as well.Prevents blood clots. Heparin is a good anticoagulant that prevents blood clots. However, you'll need to get frequent blood tests to make sure it's working well.
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Reviews & ratings
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Side effects
  • Headache 10%
  • Abdominal pain 6%
  • Nausea 6%
  • Diarrhea 3%
  • Indigestion 3%
  • Hemorrhage nos 2%
  • Back pain 1%
  • Dizziness 1%
  • Black "tarry" stools 1%
  • Feeling unwell 1%
More Aggrenox side effects »

We haven’t found good data for Heparin side effects.

FDA side effect reports for Heparin »
How it works
Aggrenox (Aspirin / Dipyridamole) is an antiplatelet blood thinner. It is a combination medication with two ingredients, aspirin and dipyridamole. Both make it harder for your body to form blood clots.Heparin is an anticoagulant that binds with proteins and platelets to stop blood clots from being made and traveling to the brain, heart, and lungs.
Type of medication
Prescription only
Prescription only
Available as
  • Pill
  • Injection
Used for (click to learn more)
Risk factors for serious side effects
  • Children 18 years or younger recovering from viral infections
  • History of stomach bleeding or ulcers
  • Age 60 or older
  • Also taking other blood thinners
  • Drinking 3 or more alcoholic drinks a day
  • Asthma
  • Rhinitis
  • Nasal Polyps
  • Aspirin Allergy
  • NSAID Allergy
    • Hemophilia
    • von Willebrand's disease
    • low blood platelet count
    • Also taking other blood thinners
    • History of stroke or TIA
    • Liver disease
    • Coronary artery disease
    • Angina
    • Prior heart attack
    • Coronary artery disease
    • Angina
    • History of heart attack
    • History of heart bypass surgery
    • History of coronary artery stent placement
      • Prior episodes of low blood pressure
      • Taking blood pressure medications
      • Severe kidney disease
      Detailed Aggrenox (Aspirin / Dipyridamole) risks & warnings »
      • History of bleeding problems
      • Severe high blood pressure
      • Older age
      • Heparin-induced thrombocytopenia
      Detailed Heparin risks & warnings »
      Pregnancy category
      DFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      No specific alcohol-related info.No specific alcohol-related info.
      • Do not crush or chew capsules. Can take with or without food.
      No specific food-related info.
      Kidneys and liver
      • Do not use Aggrenox (Aspirin / Dipyridamole) if you have severe kidney disease.
      No specific kidneys and liver-related info.
      No specific sex-related info.No specific sex-related info.
      No specific sleep-related info.No specific sleep-related info.
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      • This helps to prevent strokes for people who had a stroke or TIA (transient ischemic attack) before.
      • In clinical studies, Aggrenox (Aspirin / Dipyridamole) lowered the chance of another stroke for a person with a previous stroke or mini-stroke (TIA) by 36%.
      • Works better than either aspirin or dipyridamole alone to prevent strokes.
      • Works as well as Plavix (clopidogrel), another antiplatelet medication, to prevent stroke.
      • Safe to use in pregnancy and if you're breast feeding.
      • There are other medications that can help stop unexpected bleeding while taking Heparin.
      • Available as a generic medication.
      • Usually used in the hospital, but can be given at home too.
      Downsides and risks
      • Raises your risk for bleeding and bruising.
      • Has to be taken twice a day unlike Plavix that only has to be taken once daily.
      • Can be more expensive than other alternatives that are available as a generic.
      • Can't be used by people with an aspirin allergy, or a history of stomach ulcers.
      • You'll need to get labs/blood draws done on a regular basis to make sure the drug is working and to make sure you don't get unexpected side effects.
      • You can be at higher risk for bleeding or clotting while taking Heparin compared to other anticoagulants.
      Tips from our pharmacists for people taking the medication
      • Take twice daily.
      • Do not crush or chew capsules. Can take with or without food.
      • Aggrenox (Aspirin / Dipyridamole) can cause unexpected bleeding or bruising.
      • Don't take if you're allergic to aspirin.
      • Headache is a common side effect, but it often goes away after the first week of use.
      • Make sure to change where you inject Heparin every time.
      • Don't take aspirin or other anti-inflammatory medications without talking to your doctor first.
      • You will have to do regular blood draws or labs to make sure that Heparin is working for you.
      Learn more
      More about AggrenoxSide effectsReviews & ratingsAlternativesFDA package insert
      More about HeparinSide effectsReviews & ratingsAlternativesFDA package insert