Compare Aggrenox vs. Xarelto

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prevents blood clots that can cause a stroke.

Aggrenox (Aspirin / Dipyridamole) prevents blood clots and stroke, but cheaper options are available that work just as well.

Prevents blood clots.

Xarelto (rivaroxaban) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. However, it can be expensive and there's no way to reverse the medication's effects.

3.5/ 5 average rating with 22 reviewsforXarelto
Upsides
  • This helps to prevent strokes for people who had a stroke or TIA (transient ischemic attack) before.
  • In clinical studies, Aggrenox (Aspirin / Dipyridamole) lowered the chance of another stroke for a person with a previous stroke or mini-stroke (TIA) by 36%.
  • Works better than either aspirin or dipyridamole alone to prevent strokes.
  • Works as well as Plavix (clopidogrel), another antiplatelet medication, to prevent stroke.
  • Studies show that Xarelto (rivaroxaban) works just as well as other blood thinners (anticoagulants) in preventing strokes and stopping clots from froming.
  • Xarelto (rivaroxaban) doesn't require regular blood tests or frequent dose changes.
  • Xarelto (rivaroxaban) doesn't interact with as many types of food as other blood thinners like warfarin (Coumadin).
Downsides
  • Raises your risk for bleeding and bruising.
  • Has to be taken twice a day unlike Plavix that only has to be taken once daily.
  • Can be more expensive than other alternatives that are available as a generic.
  • Can't be used by people with an aspirin allergy, or a history of stomach ulcers.
  • Xarelto (rivaroxaban) can increase your risk of bleeding, so call your doctor right away if you see blood in your spit, urine, or stool (look for black, tarry stools or bright red blood).
  • Xarelto (rivaroxaban) isn't available as a generic medication.
  • There are no antidotes to stop bleeding caused by taking too much Xarelto (rivaroxaban).
  • You can't take Xarelto (rivaroxaban) if you are pregnant.
Used for
Dosage forms
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Reviews
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22 reviews so far
45%
saidit'sworth it
45%
saiditworked well
9%
saidit'sa big hassle

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Side effects
27possible side effects
  • Headache
    40%
  • Dyspepsia
    20%
  • Abdominal Pain
    20%
  • Nausea
    20%
  • Diarrhea
    13%
  • Vomiting
    8%
  • Pain
    6%
  • Fatigue
    6%
  • Arthralgia
    6%
  • Back Pain
    5%
  • Dizziness
    5%
  • Accidental Injury
    3%
  • Hemorrhage NOS
    3%
  • Convulsions
    2%
  • Hemorrhage Rectum
    2%
  • Melena
    2%
  • Malaise
    2%
  • Asthenia
    2%
  • Amnesia
    2%
  • Arthritis
    2%
  • Coughing
    2%
  • Cardiac Failure
    2%
  • Epistaxis
    2%
  • Neoplasm NOS
    2%
  • Anemia
    2%
  • Stroke
    2%
  • Transient Ischemic Attack
    2%
See more detailed side effects
2possible side effects
  • Major bleeding needing transfusion
    4%
  • Bleeding in the stomach & intestines
    2%
See more detailed side effects
Risks and risk factors
  • Brain damage or death from Reyes Syndrome
    • Children 18 years or younger recovering from viral infections
  • Stomach bleeding
    • History of stomach bleeding or ulcers
    • Age 60 or older
    • Also taking other blood thinners
    • Drinking 3 or more alcoholic drinks a day
  • Serious allergic reactions
    • Asthma
    • Rhinitis
    • Nasal Polyps
    • Aspirin Allergy
    • NSAID Allergy
  • Harm to unborn babies
  • Bruising or bleeding
    • Hemophilia
    • von Willebrand's disease
    • low blood platelet count
    • Also taking other blood thinners
    • History of stroke or TIA
    • Liver disease
  • Worsening heart disease
    • Coronary artery disease
    • Angina
    • Prior heart attack
  • Taking the wrong aspirin dose for heart protection
    • Coronary artery disease
    • Angina
    • History of heart attack
    • History of heart bypass surgery
    • History of coronary artery stent placement
  • Liver damage
  • Low blood pressure
    • Prior episodes of low blood pressure
    • Taking blood pressure medications
  • Kidney damage
    • Severe kidney disease
See more detailed risks and warnings
  • Blood clots and stroke
    • Stopping Xarelto (rivaroxaban) too soon
    • Artificial heart valve
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Age 65 or older
    • Drug interactions
    • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Increased side effects
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings