Compare Aldactazide vs. spironolactone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aldactazide
(spironolactone / hydrochlorothiazide)

Aldactone
(spironolactone)

Lowers blood pressure. Removes extra water from your body. Aldactazide (Spironolactone / Hydrochlorothiazide) removes excess fluid in your body and lowers your blood pressure, while helping keep your potassium levels safe.Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Aldactazide (spironolactone / hydrochlorothiazide)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it
Side effects
Aldactazidespironolactone

We haven’t found good data for Aldactazide side effects.

FDA side effect reports for Aldactazide »

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »
How it works
Aldactazidespironolactone
Aldactazide (Spironolactone / Hydrochlorothiazide) is a combination medicine that lowers your blood pressure with two diuretics (water pills), hydrochlorothiazide and spironolactone. They act on different parts of your kidney to get rid of extra fluids.Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.
Type of medication
Aldactazidespironolactone
Prescription onlyPrescription only
Available as
Aldactazidespironolactone
  • Pill
  • Pill
Used for
Aldactazidespironolactone
Risk factors for serious side effects
Aldactazidespironolactone
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
  • Medicine that affects electrolytes
Detailed Aldactazide (spironolactone / hydrochlorothiazide) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that lower your blood pressure
  • Current kidney problems
  • Taking other medicines that increase potassium
  • Use of salt substitutes
Detailed Aldactone (spironolactone) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
Aldactazidespironolactone
  • Aldactazide (Spironolactone / Hydrochlorothiazide) can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.
  • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
  • Needs blood tests to monitor electrolytes and kidney function.
  • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
Pain
Aldactazidespironolactone
No pain related info.
  • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
Upsides and benefits
Aldactazidespironolactone
  • Lowers the risk of heart attack and stroke.
  • Has a low risk of causing muscle problems due to low potassium levels in your blood.
  • Gets rid of extra fluids in your body.
  • Helpful for people who tend to have low potassium levels.
  • Has a low risk of causing muscle problems from low potassium levels in your blood.
  • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
  • Can lower blood pressure.
  • Reduces the risk of death in people with heart failure.
Downsides and risks
Aldactazidespironolactone
  • Many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • Needs blood tests to monitor electrolytes and kidney function.
  • Can make you urinate more often.
  • Can make you sensitive to sunlight.
  • Shouldn't take it if you have a sulfa allergy.
  • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
  • Has many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
Tips from our pharmacists for people taking the medication
Aldactazidespironolactone
  • Makes you urinate more often, so don't take it at bedtime.
  • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how it affects you.
  • Don't use supplements or salt substitutes that are high in potassium.
  • Get your blood pressure, potassium, and kidney function checked one week after starting the medicine, then routinely after.
  • Tell your doctor about any dizziness, muscle weakness, skin changes, red or black tarry stool.
  • Can make your skin more sensitive to sun, so use proper protections.
  • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
  • Don't use supplements or salt substitutes that are high in potassium.
  • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
  • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
  • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
Learn more
More about AldactazideSide effectsAlternativesFDA package insert
Have you used Aldactazide (spironolactone / hydrochlorothiazide)?
Worth itNot sureNot worth it
More about spironolactoneSide effectsAlternativesFDA package insert
Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it