Compare Aldactone vs. Edecrin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Aldactone
(Spironolactone)

Edecrin
(Ethacrynic Acid)

Removes extra water from your body. Aldactone (Spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.Coming soon.
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Reviews & ratings
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Have you used Aldactone (Spironolactone)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Edecrin (Ethacrynic Acid)?
Worth itNot sureNot worth it
Side effects
AldactoneEdecrin

The Aldactone FDA package insert doesn’t have numbers about how common side effects are.

More about Aldactone side effects »

We haven’t found good data for Edecrin side effects.

FDA side effect reports for Edecrin »
How it works
AldactoneEdecrin
Aldactone (Spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.
Type of medication
AldactoneEdecrin
Antihypertensive
Aldosterone antagonist
Prescription only
Coming soon.
Available as
AldactoneEdecrin
  • Pill
  • Pill
Used for (click to learn more)
AldactoneEdecrin
  • Edema
Risk factors for serious side effects
AldactoneEdecrin
  • Taking with alcohol
  • Taking other medicines that lower your blood pressure
  • Current kidney problems
  • Taking other medicines that increase potassium
  • Use of salt substitutes
Detailed risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Kidneys and liver
AldactoneEdecrin
  • You'll need to have blood tests done regularly since Aldactone (Spironolactone) can affect your potassium levels and kidneys.
No kidneys and liver related info.
Pain
AldactoneEdecrin
  • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
No pain related info.
Upsides and benefits
AldactoneEdecrin
  • Has a low risk of causing muscle problems from low potassium levels in your blood.
  • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
  • Can lower blood pressure.
  • Reduces the risk of death in people with heart failure.
Coming soon
Downsides and risks
AldactoneEdecrin
  • Aldactone (Spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
  • Has many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • You'll need to have blood tests done regularly since Aldactone (Spironolactone) can affect your potassium levels and kidneys.
Coming soon
Tips from our pharmacists for people taking the medication
AldactoneEdecrin
  • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
  • Don't use supplements or salt substitutes that are high in potassium.
  • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
  • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
  • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
Coming soon
Learn more
More about AldactoneSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Aldactone (Spironolactone)?
Worth itNot sureNot worth it
More about EdecrinSide effectsFDA package insert
Have you used Edecrin (Ethacrynic Acid)?
Worth itNot sureNot worth it