Compare spironolactone vs. Triamterene

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Removes extra water from your body.

Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.

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Upsides
  • Has a low risk of causing muscle problems from low potassium levels in your blood.
  • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
  • Can lower blood pressure.
  • Reduces the risk of death in people with heart failure.
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Downsides
  • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
  • Has many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
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Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
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Side effects
The Aldactone (spironolactone) FDA package insert doesn’t have numbers about how common side effects are.
The Dyrenium (Triamterene) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Tumor development
  • Low blood pressure
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
  • Heart problems from high potassium
    • Current kidney problems
    • Taking other medicines that increase potassium
    • Use of salt substitutes
  • Breast pain or swelling
See more detailed risks and warnings
No information currently available