Compare spironolactone vs. Triamterene

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Aldactone
(spironolactone)

Dyrenium
(triamterene)

Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.Coming soon.
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Best available price for 30 (25mg) tablets of spironolactone
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Reviews & ratings
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Reviews for Aldactone (spironolactone)
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of people (All ages) say Aldactone (spironolactone) is worth it
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say it works well
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say it's a big hassle
Have you used Aldactone (spironolactone)?
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Reviews for Dyrenium (triamterene)
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Same vs. Aldactone (spironolactone)
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Same vs. Aldactone (spironolactone)
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Same vs. Aldactone (spironolactone)
Have you used Dyrenium (triamterene)?
Worth itNot sureNot worth it
Side effects
spironolactoneTriamterene

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »

We haven’t found good data for Triamterene side effects.

FDA side effect reports for Triamterene »
How it works
spironolactoneTriamterene
Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.Coming soon.
Type of medication
spironolactoneTriamterene
Prescription only
Available as
spironolactoneTriamterene
  • Pill
  • Pill
Used for
spironolactoneTriamterene
  • Edema
Risk factors for serious side effects
spironolactoneTriamterene
  • Taking with alcohol
  • Taking other medicines that lower your blood pressure
  • Current kidney problems
  • Taking other medicines that increase potassium
  • Use of salt substitutes
Detailed Aldactone (spironolactone) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Kidneys and liver
    spironolactoneTriamterene
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    No kidneys and liver related info.
    Pain
    spironolactoneTriamterene
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    No pain related info.
    Upsides and benefits
    spironolactoneTriamterene
    • Has a low risk of causing muscle problems from low potassium levels in your blood.
    • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
    • Can lower blood pressure.
    • Reduces the risk of death in people with heart failure.
    Coming soon
    Downsides and risks
    spironolactoneTriamterene
    • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
    • Has many possible side effects, especially when higher doses are used.
    • Can increase the risk of tumor growth.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    Coming soon
    Tips from our pharmacists for people taking the medication
    spironolactoneTriamterene
    • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
    • Don't use supplements or salt substitutes that are high in potassium.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
    • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
    Coming soon
    Learn more
    More about spironolactoneSide effectsAlternativesFDA package insert
    Have you used Aldactone (spironolactone)?
    Worth itNot sureNot worth it
    More about TriamtereneSide effectsFDA package insert
    Have you used Dyrenium (triamterene)?
    Worth itNot sureNot worth it