Compare Alka-Seltzer Plus Day Severe Cold and Flu vs. Robitussin DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Alka-Seltzer Plus Day Severe Cold And Flu
(Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine)

Robitussin Dm
(Guaifenesin / Dextromethorphan)

Relieves cold and flu symptoms. Alka-Seltzer Plus Day Severe Cold And Flu (Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine) is okay for multiple cold symptoms, but it's more medicine than you need if you only have one symptom.Breaks up mucus and relieves cough. Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.
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Reviews & ratings
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Reviews for Robitussin Dm (Guaifenesin / Dextromethorphan)
75%
+75% vs. Alka-Seltzer Plus Day Severe Cold And Flu (Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine)
37%
+37% vs. Alka-Seltzer Plus Day Severe Cold And Flu (Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine)
7%
7% vs. Alka-Seltzer Plus Day Severe Cold And Flu (Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine)
Side effects
Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM

We haven’t found good data for Alka-Seltzer Plus Day Severe Cold and Flu side effects.

FDA side effect reports for Alka-Seltzer Plus Day Severe Cold and Flu »

We haven’t found good data for Robitussin DM side effects.

FDA side effect reports for Robitussin DM »
How it works
Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
Alka-Seltzer Plus Day Severe Cold And Flu (Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine) is a combination medicine that treats cold and flu symptoms. Acetaminophen relieves pain and reduces fever. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses. Guaifenesin breaks up mucus and phlegm.Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.
Type of medication
Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
Pain reliever
Acetaminophen (APAP)
Cough suppressantExpectorantDecongestantOver-the-counter
ExpectorantCough suppressantOver-the-counter
Available as
Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
  • Powder
  • Liquid
  • Pill
  • Liquid
Used for (click to learn more)
Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
Risk factors for serious side effects
Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
  • History of high blood pressure
  • Taking MAO inhibitors
  • History of chronic obstructive pulmonary disease (COPD)
  • History of smoking
  • Using other medications that affect serotonin
Detailed Alka-Seltzer Plus Day Severe Cold And Flu (Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine) risks & warnings »
    • Using other medications that affect serotonin
      Detailed Robitussin Dm (Guaifenesin / Dextromethorphan) risks & warnings »
      Pregnancy category
      Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
      NFDA pregnancy category (Unknown)

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      See the FDA package insert
      NFDA pregnancy category (Unknown)

      The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.No specific alcohol-related info.
      Food
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
      • Alka-Seltzer Plus Day Severe Cold And Flu (Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
      • The decongestant (phenylephrine) has fewer side effects than other decongestants. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
      • The cough medicine (dextromethorphan) works well and has very few side effects.
      • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
      • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
      • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
      Downsides and risks
      Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
      • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
      • Guaifenesin isn’t useful if you have a dry cough without chest congestion.
      • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
      • You shouldn't use it if you have high blood pressure.
      • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
      • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
      • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
      • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
      • Can cause sleepiness, dizziness, and an upset stomach.
      Tips from our pharmacists for people taking the medication
      Alka-Seltzer Plus Day Severe Cold and FluRobitussin DM
      • Alka-Seltzer Plus Day Severe Cold And Flu (Acetaminophen / Dextromethorphan / Guaifenesin / Phenylephrine) comes as a powder packet you can dissolve in hot water and drink.
      • Phenylephrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
      • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
      • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.
      • Drink plenty of fluids while taking Robitussin Dm (Guaifenesin / Dextromethorphan) because liquid helps break down mucus.
      • Cough suppressant starts working in 15 to 30 minutes.
      • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
      • If your cough lasts more than 7 days, call your doctor.
      Learn more
      More about Alka-Seltzer Plus Day Severe Cold and FluSide effectsAlternativesFDA package insert
      More about Robitussin DMSide effectsReviews & ratingsAlternativesFDA package insert