Compare Allegra-D vs. Advil Congestion Relief

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Allegra-D (fexofenadine / pseudoephedrine)

Over-the-counter
Treats allergy symptoms and congestion.

Allegra-D (fexofenadine / pseudoephedrine) is a combination allergy medicine that's useful if you have congestion and runny nose.

Relieves pain and congestion.

Advil Congestion Relief (Ibuprofen / Phenylephrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.

4.9/ 7 average rating with 1125 reviewsforAdvil Congestion Relief
Upsides
  • Allegra-D (fexofenadine / pseudoephedrine) contains two medicines that work in different ways to help relieve multiple symptoms including nasal congestion and allergies.
  • Available without a prescription in the drugstore.
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
Downsides
  • You must show a photo ID to purchase this medicine from behind the pharmacy counter. There's a maximum limit on how much Allegra-D (fexofenadine / pseudoephedrine) you can buy at a time.
  • Allegra-D (fexofenadine / pseudoephedrine) can have more side effects (such as increased blood pressure and difficulty sleeping) than Allegra since it has pseudoephedrine in it.
  • If you have severe high blood pressure or heart disease you can't take this medicine. If you have kidney damage, you may not be able to take Allegra-D (fexofenadine / pseudoephedrine).
  • If you don't really need both of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
Used for
Dosage forms
  • Pill
  • Pill
No pricing information available
No pricing information available
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Reviews
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1125 
73%
think this treatment is worth it
32%
think this treatment works well
7%
think this treatment is a hassle

Have you used Advil Congestion Relief (Ibuprofen / Phenylephrine)?

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Side effects
10possible side effects
  • Headache
    13%
  • Trouble sleeping
    13%
  • Nausea
    7%
  • Dry Mouth
    3%
  • Indigestion
    3%
  • Throat irritation
    2%
  • Dizziness
    2%
  • Agitation
    2%
  • Back pain
    2%
  • Palpitations
    2%
See more detailed side effects
The Advil Congestion Relief (Ibuprofen / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • High blood pressure

    History of high blood pressure

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

  • Seizure

    History of seizure

See more detailed risks and warnings
  • Stomach bleeding

    History of stomach bleeding or ulcers

    ...and 3 more risk factors

  • Harm to fetus

    Women of childbearing age

  • High blood pressure

    History of high blood pressure

  • Lower kidney function

    Kidney disease

    ...and 4 more risk factors

  • Heart attack or stroke

    History of heart problems

    ...and 2 more risk factors

See more detailed risks and warnings