Compare Allegra-D vs. Flonase

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Allegra-D (fexofenadine / pseudoephedrine)

Over-the-counter

Flonase (Fluticasone)

Prescription or OTC
Treats allergy symptoms and congestion.

Allegra-D (fexofenadine / pseudoephedrine) is a combination allergy medicine that's useful if you have congestion and runny nose.

Relieves allergy symptoms.

Flonase (Fluticasone) is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives.

5.0/ 7 average rating with 890 reviewsforFlonase
Upsides
  • Allegra-D (fexofenadine / pseudoephedrine) contains two medicines that work in different ways to help relieve multiple symptoms including nasal congestion and allergies.
  • Available without a prescription in the drugstore.
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic medication.
Downsides
  • You must show a photo ID to purchase this medicine from behind the pharmacy counter. There's a maximum limit on how much Allegra-D (fexofenadine / pseudoephedrine) you can buy at a time.
  • Allegra-D (fexofenadine / pseudoephedrine) can have more side effects (such as increased blood pressure and difficulty sleeping) than Allegra since it has pseudoephedrine in it.
  • If you have severe high blood pressure or heart disease you can't take this medicine. If you have kidney damage, you may not be able to take Allegra-D (fexofenadine / pseudoephedrine).
  • Flonase (Fluticasone) doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Needs to be primed (pressed/pumped until a fine spray appears) up to six times prior to using it for the first time, or if you haven't used it in 2 weeks.
  • Since the medicine in Flonase (Fluticasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
Used for
Dosage forms
  • Pill
  • Nasal spray
Price
No pricing information available
Lowest price near you
$200.08
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Reviews
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890 
72%
think this treatment is worth it
43%
think this treatment works well
7%
think this treatment is a hassle

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Side effects
10possible side effects
  • Headache
    13%
  • Trouble sleeping
    13%
  • Nausea
    7%
  • Dry Mouth
    3%
  • Indigestion
    3%
  • Throat irritation
    2%
  • Dizziness
    2%
  • Agitation
    2%
  • Back pain
    2%
  • Palpitations
    2%
See more detailed side effects
The Flonase (Fluticasone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • High blood pressure

    History of high blood pressure

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

  • Seizure

    History of seizure

See more detailed risks and warnings
  • Adrenal suppression

    Switching from oral or injectable steroids to inhaled, especially if used long term

    ...and 1 more risk factors

  • Decrease in growth in children and teenagers

    Long-term use

    ...and 1 more risk factors

  • Adrenal suppression

    Switching from oral or injectable steroids to inhaled, especially if used long term

    ...and 1 more risk factors

  • Thrush in the nose and throat

    Long-term use

  • Reduced immune system

    Exposure to immunizable diseases (chickenpox and measles)

    ...and 1 more risk factors

  • Decreased wound healing

    Surgery or trauma to the nose or sinuses

  • Changes in the nasal septum

    Long-term use

See more detailed risks and warnings