Compare Allegra-D vs. Phenylephrine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats allergy symptoms and congestion.

Allegra-D (fexofenadine / pseudoephedrine) is a combination allergy medicine that's useful if you have congestion and runny nose.

Clears your sinuses.

Sudafed Pe (Phenylephrine) is a good medication for relieving stuffy nose. It doesn't work as well as pseudoephedrine (Sudafed), but it has fewer side effects.

3.1/ 5 average rating with 164 reviewsforPhenylephrine
Upsides
  • Allegra-D (fexofenadine / pseudoephedrine) contains two medicines that work in different ways to help relieve multiple symptoms including nasal congestion and allergies.
  • Available without a prescription in the drugstore.
  • Works to clear nasal congestion and helps you breathe better.
  • Helpful in relieving congestion-related headaches.
  • Has fewer side effects than other decongestants like pseudoephedrine.
  • It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Doesn't give you rebound congestion (worse symptoms when you stop taking it) like nasal spray decongestants do.
Downsides
  • You must show a photo ID to purchase this medicine from behind the pharmacy counter. There's a maximum limit on how much Allegra-D (fexofenadine / pseudoephedrine) you can buy at a time.
  • Allegra-D (fexofenadine / pseudoephedrine) can have more side effects (such as increased blood pressure and difficulty sleeping) than Allegra since it has pseudoephedrine in it.
  • If you have severe high blood pressure or heart disease you can't take this medicine. If you have kidney damage, you may not be able to take Allegra-D (fexofenadine / pseudoephedrine).
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine (Sudafed).
  • You shouldn't use it if you have high blood pressure.
  • Can make your heart race or make you feel anxious and restless.
  • Shouldn't use it before you want to sleep.
  • Not as effective after using it for 4 days in a row.
Used for
Dosage forms
  • Pill
  • Pill
  • Nasal spray
  • Eye drops
  • Suppository
Price
No pricing information available
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Reviews
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164 reviews so far
44%
saidit'sworth it
24%
saiditworked well
10%
saidit'sa big hassle

Have you used Sudafed Pe (Phenylephrine)?

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Side effects
10possible side effects
  • Headache
    13%
  • Trouble sleeping
    13%
  • Nausea
    7%
  • Dry Mouth
    3%
  • Indigestion
    3%
  • Throat irritation
    2%
  • Dizziness
    2%
  • Agitation
    2%
  • Back pain
    2%
  • Palpitations
    2%
See more detailed side effects
The Sudafed Pe (Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • High blood pressure
    • History of high blood pressure
  • Heart problems
    • History of heart problems
    • Age 65 or older
  • Seizure
    • History of seizure
See more detailed risks and warnings
  • High blood pressure
    • History of high blood pressure
    • Taking MAO inhibitors
  • Heart problems
    • History of heart problems
    • Age 65 years or older
  • Harm to fetus
    • Women of childbearing age
See more detailed risks and warnings