Compare Allegra vs. Advil Allergy And Congestion Relief

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Allegra (Fexofenadine)

Prescription or OTC
Treats allergy symptoms.

Allegra (Fexofenadine) relieves allergy symptoms without making you feel drowsy.

5.4/ 7 average rating with 24 reviewsforAllegra
Relieves cold and allergy symptoms.

Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is an okay combination medicine to relieve pain and congestion. The antihistamine can make you sleepy and the decongestant can keep you awake, so it could affect you either way.

4.9/ 7 average rating with 1437 reviewsforAdvil Allergy And Congestion Relief
Upsides
  • Relieves allergy symptoms, like sneezing, runny nose, and itching.
  • Approved to be used in kids and adults age 6 months and older.
  • Won't make you feel drowsy like some antihistamine medicines.
  • Available over-the-counter without a prescription.
  • Comes in many forms, such as a tablet, liquid, or quick-dissolving tablet.
  • It's okay to take with most other medications since it has very few interactions.
  • Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
Downsides
  • For some people, the effects Allegra (Fexofenadine) has on allergies will wear off over time.
  • May not work as well as the first-generation antihistamines, like diphenhydramine (Benadryl).
  • The dose needs to be adjusted for people with kidney problems.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Liquid
  • Pill
No pricing information available
No pricing information available
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Reviews
24 
79%
think this treatment is worth it
63%
think this treatment works well
0%
think this treatment is a hassle

Have you used Allegra (Fexofenadine)?

Leave a review
1437 
73%
think this treatment is worth it
30%
think this treatment works well
6%
think this treatment is a hassle

Have you used Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine)?

Leave a review
Side effects
4possible side effects
  • Dizziness
    2%
  • Back Pain
    2%
  • Stomach Discomfort
    2%
  • Pain in extremity
    2%
See more detailed side effects
The Advil Allergy And Congestion Relief (Chlorpheniramine / Ibuprofen / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Brain damage from too much phenylalanine

    History of phenylketonuria (PKU)

See more detailed risks and warnings
  • Stomach bleeding

    History of stomach bleeding or ulcers

    ...and 3 more risk factors

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Harm to fetus

    Women of childbearing age

  • Lower kidney function

    Kidney disease

    ...and 4 more risk factors

  • High blood pressure

    History of high blood pressure

  • Heart attack or stroke

    History of heart problems

    ...and 2 more risk factors

See more detailed risks and warnings