Compare Allegra vs. Allegra D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Allegra
(Fexofenadine)

Allegra D
(Pseudoephedrine / Fexofenadine)

Treats allergy symptoms. Allegra (Fexofenadine) relieves allergy symptoms without making you feel drowsy.Treats allergy symptoms and congestion. Allegra D (Pseudoephedrine / Fexofenadine) is a combination allergy medicine that's useful if you have congestion and runny nose.
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Reviews & ratings
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5.2727272727272725Allegra
Reviews for Allegra (Fexofenadine)
77%
of people say Allegra (Fexofenadine) is worth it
59%
say it works well
0%
say it's a big hassle

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Side effects
AllegraAllegra D
  • Vomiting 3%
  • Headache 3%
  • Cough 3%
  • Back pain 2%
  • Ear, nose, or throat infection 2%
  • Diarrhea 1%
  • Fever 1%
  • Runny nose 1%
  • Dizziness 1%
  • Stomach discomfort 1%
More Allegra side effects »
  • Back pain 2%
More Allegra D side effects »
How it works
AllegraAllegra D
Allegra (Fexofenadine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions.Allegra D (Pseudoephedrine / Fexofenadine) is a combination medicine that relieves allergy symptoms. Fexofenadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itching. Pseudoephedrine (a decongestant) clears your sinuses.
Type of medication
AllegraAllegra D
Antihistamine
2nd generation
Prescription or OTC
DecongestantAntihistamine
2nd generation
Prescription or OTC
Available as
AllegraAllegra D
  • Pill
  • Dissolving tablet
  • Liquid
  • Extended release
Used for (click to learn more)
AllegraAllegra D
Risk factors for serious side effects
AllegraAllegra D
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • History of phenylketonuria (PKU)
Detailed Allegra (Fexofenadine) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • History of high blood pressure
  • History of heart problems
  • Age 65 or older
  • History of seizure
  • Women of childbearing age
Detailed Allegra D (Pseudoephedrine / Fexofenadine) risks & warnings »
Pregnancy category
AllegraAllegra D
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
  • The dose needs to be adjusted for people with kidney problems.
  • Talk to your doctor if you have high blood pressure or kidney problems before using it.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
  • Won't make you feel drowsy like some antihistamine medicines.
  • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • The decongestant (pseudoephedrine) can make your blood pressure higher and can make it harder to sleep.
  • Avoid taking it close to bedtime to prevent trouble sleeping.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
AllegraAllegra D
  • Relieves allergy symptoms, like sneezing, runny nose, and itching.
  • Approved to be used in kids and adults age 6 months and older.
  • Won't make you feel drowsy like some antihistamine medicines.
  • Available over-the-counter without a prescription.
  • Comes in many forms, such as a tablet, liquid, or quick-dissolving tablet.
  • It's okay to take with most other medications since it has very few interactions.
  • Available without a prescription in the drugstore.
  • It has two medications that work in different ways to help relieve nasal symptoms.
  • The antihistamine (fexofenadine) is useful for relieving itchy eyes, runny nose, or constant sneezing.
  • The decongestant (pseudoephedrine) is very good at relieving congestion.
Downsides and risks
AllegraAllegra D
  • For some people, the effects Allegra (Fexofenadine) has on allergies will wear off over time.
  • May not work as well as the first-generation antihistamines, like diphenhydramine (Benadryl).
  • The dose needs to be adjusted for people with kidney problems.
  • Has more side effects than Allegra since it has pseudoephedrine in it.
  • The antihistamine (fexofenadine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • The decongestant (pseudoephedrine) can make your blood pressure higher and can make it harder to sleep.
  • You must show a photo ID to buy this from behind the pharmacy counter. There's a maximum limit on how much you can buy in the pharmacy at a time.
Tips from our pharmacists for people taking the medication
AllegraAllegra D
  • Starts working in 1 to 2 hours depending on what dosage form you're taking.
  • Works best when taken regularly, even before symptoms are expected to appear.
  • Can make you feel dizzy or sleepy, so you can take it at bedtime.
  • Follow age-specific dosing and don't take more than recommended.
  • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
  • It works best if you have nasal congestion and a runny nose.
  • Take on an empty stomach, 1 hour before eating or 2 hours after eating.
  • Shouldn't be used in kids younger than 12 years old.
  • Avoid taking it close to bedtime to prevent trouble sleeping.
  • Can cause dizziness, headache, or a fast heartbeat.
  • Talk to your doctor if you have high blood pressure or kidney problems before using it.
  • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
Learn more
More about AllegraSide effectsReviews & ratingsAlternativesFDA package insert
More about Allegra DSide effectsReviews & ratingsAlternativesFDA package insert