Compare Allegra vs. Claritin D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Allegra
(fexofenadine)

Claritin D
(loratadine / pseudoephedrine)

Treats allergy symptoms. Allegra (Fexofenadine) relieves allergy symptoms without making you feel drowsy.Relieves congestion and allergy symptoms. Claritin D (Loratadine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.
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Coupons for Allegra
Best available price for 30 (24 hour) tablets of allegra
Coupons for Claritin D
Best available price for 60 (12 hour) tablets of claritin-d
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.38Allegra
Reviews for Allegra
79%
of people (All ages) say Allegra is worth it
63%
say it works well
0%
say it's a big hassle
Have you used Allegra (fexofenadine)?
Worth itNot sureNot worth it
Reviews for Claritin D
69%
+10% better vs. Allegra
39%
+24% better vs. Allegra
8%
+8% better vs. Allegra
1527 reviews
Have you used Claritin D (loratadine / pseudoephedrine)?
Worth itNot sureNot worth it
Side effects
AllegraClaritin D
  • Menstrual cramps 2%
  • Headache 3%
  • Back pain 2%
  • Cough 3%
  • Ear, nose, or throat infection 2%
  • Fever 1%
  • Middle ear inflammation 2%
  • Runny nose 1%
More Allegra side effects »

We haven’t found good data for Claritin D side effects.

FDA side effect reports for Claritin D »
How it works
AllegraClaritin D
Allegra (Fexofenadine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions.Claritin D (Loratadine / Pseudoephedrine) is a combination medicine for allergies. Loratadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.
Type of medication
AllegraClaritin D
Prescription or OTCPrescription or OTC
Available as
AllegraClaritin D
  • Pill
  • Dissolving tablet
  • Liquid
  • Extended release
Used for
AllegraClaritin D
Risk factors for serious side effects
AllegraClaritin D
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • History of phenylketonuria (PKU)
Detailed Allegra (fexofenadine) risks & warnings »
  • History of high blood pressure
  • History of heart problems
  • Age 65 or older
  • History of seizure
  • Women of childbearing age
Detailed Claritin D (loratadine / pseudoephedrine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Food
AllegraClaritin D
  • Some forms of Allegra (Fexofenadine) contain aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, check to see which products you can use.
  • Claritin D (Loratadine / Pseudoephedrine) contains aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, don't use this product.
Kidneys and liver
AllegraClaritin D
  • The dose needs to be adjusted for people with kidney problems.
No kidneys and liver related info.
Sleep
AllegraClaritin D
  • Can make you feel dizzy or sleepy, so you can take it at bedtime.
  • Won't make you feel drowsy like some antihistamine medicines.
  • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
Upsides and benefits
AllegraClaritin D
  • Relieves allergy symptoms, like sneezing, runny nose, and itching.
  • Approved to be used in kids and adults age 6 months and older.
  • Won't make you feel drowsy like some antihistamine medicines.
  • Available over-the-counter without a prescription.
  • Comes in many forms, such as a tablet, liquid, or quick-dissolving tablet.
  • It's okay to take with most other medications since it has very few interactions.
  • The antihistamine (Loratadine) in Claritin D (Loratadine / Pseudoephedrine) works as well as other antihistamines, but causes less drowsiness. It's also less sedating than Allegra D and Zyrtec D.
  • The decongestant (Pseudoephedrine) in Claritin D (Loratadine / Pseudoephedrine) is stronger than other decongestants. It can also help relieve congestion-related headaches and ear pressure.
  • The stimulant effects of Pseudoephedrine can give you some extra energy during the day.
  • Doesn't give you rebound congestion (worse congestion symptoms after you stop taking the medicine) like decongestant nose sprays can.
  • It's available without a prescription, unlike other strong allergy medicines.
Downsides and risks
AllegraClaritin D
  • For some people, the effects Allegra (Fexofenadine) has on allergies will wear off over time.
  • May not work as well as the first-generation antihistamines, like diphenhydramine (Benadryl).
  • The dose needs to be adjusted for people with kidney problems.
  • You can have more side effects when using combination pills than when using single-ingredient medications.
  • The decongestant (Pseudoephedrine) can make your heart race or give you anxious or restless feelings.
  • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
  • Pseudoephedrine can raise your blood pressure, so don't take it if you have high blood pressure or other heart conditions.
  • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
Tips from our pharmacists for people taking the medication
AllegraClaritin D
  • Starts working in 1 to 2 hours depending on what dosage form you're taking.
  • Works best when taken regularly, even before symptoms are expected to appear.
  • Can make you feel dizzy or sleepy, so you can take it at bedtime.
  • Follow age-specific dosing and don't take more than recommended.
  • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
  • Starts working in 30 minutes.
  • You need to show an ID to buy Claritin D (Loratadine / Pseudoephedrine) in the drugstore because it contains Pseudoephedrine.
  • Don't cut, crush, or chew tablets; swallow them whole.
  • It's better to take Claritin D (Loratadine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • If you need to use it for more than a few weeks, talk with your doctor since a different medication might work better for you.
Learn more
More about AllegraSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Allegra (fexofenadine)?
Worth itNot sureNot worth it
More about Claritin DSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Claritin D (loratadine / pseudoephedrine)?
Worth itNot sureNot worth it