Compare Allegra vs. Claritin D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Allegra
(Fexofenadine)

Claritin D
(Loratadine / Pseudoephedrine)

Treats allergy symptoms. Allegra (Fexofenadine) relieves allergy symptoms without making you feel drowsy.Relieves congestion and allergy symptoms. Claritin D (Loratadine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.
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Reviews & ratings
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Have you used Allegra (Fexofenadine)?
Worth itNot sureNot worth it
Reviews for Claritin D (Loratadine / Pseudoephedrine)
69%
8% vs. Allegra (Fexofenadine)
38%
21% vs. Allegra (Fexofenadine)
8%
8% vs. Allegra (Fexofenadine)
1516 reviews
Have you used Claritin D (Loratadine / Pseudoephedrine)?
Worth itNot sureNot worth it
Side effects
AllegraClaritin D
  • Vomiting 3%
  • Headache 3%
  • Cough 3%
  • Back pain 2%
  • Ear, nose, or throat infection 2%
  • Diarrhea 1%
  • Fever 1%
  • Runny nose 1%
  • Dizziness 1%
  • Stomach discomfort 1%
More Allegra side effects »

We haven’t found good data for Claritin D side effects.

FDA side effect reports for Claritin D »
How it works
AllegraClaritin D
Allegra (Fexofenadine) is an antihistamine. It blocks histamine, a chemical that causes congestion, itching, and other allergic reactions.Claritin D (Loratadine / Pseudoephedrine) is a combination medicine for allergies. Loratadine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Pseudoephedrine (a decongestant) clears your sinuses.
Type of medication
AllegraClaritin D
Antihistamine
2nd generation
Prescription or OTC
Antihistamine
2nd generation
DecongestantPrescription or OTC
Available as
AllegraClaritin D
  • Pill
  • Dissolving tablet
  • Liquid
  • Extended release
Used for (click to learn more)
AllegraClaritin D
Risk factors for serious side effects
AllegraClaritin D
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • History of phenylketonuria (PKU)
Detailed Allegra (Fexofenadine) risks & warnings »
  • History of high blood pressure
  • History of heart problems
  • Age 65 or older
  • History of seizure
  • Women of childbearing age
    • Age 65 years or older
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • History of phenylketonuria (PKU)
    Detailed Claritin D (Loratadine / Pseudoephedrine) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Food
    AllegraClaritin D
    • Some forms of Allegra (Fexofenadine) contain aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, check to see which products you can use.
    • Claritin D (Loratadine / Pseudoephedrine) contains aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, don't use this product.
    Kidneys and liver
    AllegraClaritin D
    • The dose needs to be adjusted for people with kidney problems.
    No kidneys and liver related info.
    Sleep
    AllegraClaritin D
    • Won't make you feel drowsy like some antihistamine medicines.
    • Can make you feel dizzy or sleepy, so you can take it at bedtime.
    • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
    Upsides and benefits
    AllegraClaritin D
    • Relieves allergy symptoms, like sneezing, runny nose, and itching.
    • Approved to be used in kids and adults age 6 months and older.
    • Won't make you feel drowsy like some antihistamine medicines.
    • Available over-the-counter without a prescription.
    • Comes in many forms, such as a tablet, liquid, or quick-dissolving tablet.
    • It's okay to take with most other medications since it has very few interactions.
    • The antihistamine (Loratadine) in Claritin D (Loratadine / Pseudoephedrine) works as well as other antihistamines, but causes less drowsiness. It's also less sedating than Allegra D and Zyrtec D.
    • The decongestant (Pseudoephedrine) in Claritin D (Loratadine / Pseudoephedrine) is stronger than other decongestants. It can also help relieve congestion-related headaches and ear pressure.
    • The stimulant effects of Pseudoephedrine can give you some extra energy during the day.
    • Doesn't give you rebound congestion (worse congestion symptoms after you stop taking the medicine) like decongestant nose sprays can.
    • It's available without a prescription, unlike other strong allergy medicines.
    Downsides and risks
    AllegraClaritin D
    • For some people, the effects Allegra (Fexofenadine) has on allergies will wear off over time.
    • May not work as well as the first-generation antihistamines, like diphenhydramine (Benadryl).
    • The dose needs to be adjusted for people with kidney problems.
    • You can have more side effects when using combination pills than when using single-ingredient medications.
    • The decongestant (Pseudoephedrine) can make your heart race or give you anxious or restless feelings.
    • You might not sleep as well due to Pseudoephedrine's effects and you can also have strange dreams while taking it.
    • Pseudoephedrine can raise your blood pressure, so don't take it if you have high blood pressure or other heart conditions.
    • Although you don't need a prescription, you do need to show a photo ID to buy this from behind the pharmacy counter.
    Tips from our pharmacists for people taking the medication
    AllegraClaritin D
    • Starts working in 1 to 2 hours depending on what dosage form you're taking.
    • Works best when taken regularly, even before symptoms are expected to appear.
    • Can make you feel dizzy or sleepy, so you can take it at bedtime.
    • Follow age-specific dosing and don't take more than recommended.
    • If symptoms get worse or you need to use it for more than a few weeks, talk with your doctor.
    • Starts working in 30 minutes.
    • You need to show an ID to buy Claritin D (Loratadine / Pseudoephedrine) in the drugstore because it contains Pseudoephedrine.
    • Don't cut, crush, or chew tablets; swallow them whole.
    • It's better to take Claritin D (Loratadine / Pseudoephedrine) early in the morning or when you wake up, otherwise you can have trouble sleeping later.
    • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
    • If you need to use it for more than a few weeks, talk with your doctor since a different medication might work better for you.
    Learn more
    More about AllegraSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Allegra (Fexofenadine)?
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    More about Claritin DSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Claritin D (Loratadine / Pseudoephedrine)?
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