Compare almotriptan vs. Cafergot

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Axert (almotriptan)

Prescription only
Treats migraine headaches.

Axert (almotriptan) is better than other similar medications for migraines for pain relief.

Treats migraine headaches.

Cafergot (ergotamine / caffeine) can treat migraines, but you're more likely to have side effects.

Upsides
  • Effective at relieving migraine pain.
  • You can take Axert (almotriptan) with or without food.
  • Axert (almotriptan) works within 30 minutes of taking it, and most people don't have to take a second dose to control their pain.
  • Axert (almotriptan) is available in generic.
  • Cafergot (ergotamine / caffeine) works better than other medicines if your migraines usually last more than 2 days or if you have more frequent migraines.
Downsides
  • Axert (almotriptan) can only treat migraines that have already started. It can't stop a migraine from happening.
  • Axert (almotriptan) is only available as a pill that must be swallowed, so taking it might be difficult for someone who has trouble swallowing during a migraine.
  • Cafergot (ergotamine / caffeine) can't stop migraines from happening. They can only treat them.
  • Cafergot (ergotamine / caffeine) can only be used for migraines. It doesn't work for other types of headaches.
  • Smoking or using products that contain nicotine can make Cafergot (ergotamine / caffeine) less effective.
Used for
Dosage forms
  • Pill
  • Pill
  • Suppository
Price
Lowest price near you
$133.91
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Lowest price near you
$653.26
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Reviews
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Side effects
1possible side effects
  • Nausea
    2%
See more detailed side effects
The Cafergot (ergotamine / caffeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Heart attack

    Heart disease

    ...and 2 more risk factors

  • Stroke

    History of a stroke

  • Medication overuse headache

    Using Axert (almotriptan) for more than 10 days a month

  • Serotonin syndrome

    Tricyclic antidepressants

    ...and 5 more risk factors

  • Increased blood pressure

    Uncontrolled high blood pressure

  • Blood vessel issues

    High blood pressure

    ...and 1 more risk factors

See more detailed risks and warnings
  • Heart and circulation problems

    Overdosing Cafergot (ergotamine / caffeine)

    ...and 1 more risk factors

  • Dependency and withdrawal

    Taking Cafergot (ergotamine / caffeine) regularly for months

See more detailed risks and warnings