Compare almotriptan vs. ergotamine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Axert (almotriptan)

Prescription only

Ergomar (ergotamine)

Prescription only
Treats migraine headaches.

Axert (almotriptan) is better than other similar medications for migraines for pain relief.

Treats migraine headaches.

Ergomar (ergotamine) has more side effects than other medicines used to treat migraines.

Upsides
  • Effective at relieving migraine pain.
  • You can take Axert (almotriptan) with or without food.
  • Axert (almotriptan) works within 30 minutes of taking it, and most people don't have to take a second dose to control their pain.
  • Axert (almotriptan) is available in generic.
  • Ergomar (ergotamine) works better than other medicines if your migraines last more than 2 days or if you have more frequent migraines.
Downsides
  • Axert (almotriptan) can only treat migraines that have already started. It can't stop a migraine from happening.
  • Axert (almotriptan) is only available as a pill that must be swallowed, so taking it might be difficult for someone who has trouble swallowing during a migraine.
  • Harmful to the fetus so avoid if you're pregnant or think you may be pregnant.
  • Doesn't prevent migraines from happening. It can only relieve them.
  • Excessive use can be dangerous and result in rebound headaches. Talk to your doctor if your headaches are worse and occurring more frequently.
  • May not be right for you if you have high blood pressure or had a heart attack.
Used for
Dosage forms
  • Pill
  • Dissolving pill
Price
No pricing information available
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Reviews
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Side effects
1possible side effects
  • Nausea
    2%
See more detailed side effects
The Ergomar (ergotamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Heart attack
    • Heart disease
    • history of chest pain/angina
    • uncontrolled high blood pressure
  • Stroke
    • History of a stroke
  • Medication overuse headache
    • Using Axert (almotriptan) for more than 10 days a month
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
  • Increased blood pressure
    • Uncontrolled high blood pressure
  • Blood vessel issues
    • High blood pressure
    • history of stroke
See more detailed risks and warnings
  • Drug interactions
    • Macrolide antibiotics
    • Protease inhibitors
  • Lowered blood flow
    • Taking Ergomar (ergotamine) more than the recommended amount daily or weekly
  • Dependency and withdrawal
    • Taking Ergomar (ergotamine) regularly for months
See more detailed risks and warnings