Compare almotriptan vs. Zomig

Head-to-head comparisons of medication uses, side effects, ratings, and more.

almotriptan

Zomig
(zolmitriptan)

Treats migraine headaches. Axert (almotriptan) is better than other similar medications for migraines for pain relief.Treats migraines. Triptans are the first-choice to treat migraines. Zomig (zolmitriptan) works just as well as other triptans for migraines.
Reviews & ratings
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Have you used Axert (almotriptan)?
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Have you used Zomig (zolmitriptan)?
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Side effects
almotriptanZomig
  • Nausea 1%
  • Headache 1%
  • Dizziness 1%
  • Sleepiness 3%
  • Vomiting 2%
More almotriptan side effects »
  • Heaviness other than chest/neck 1%
  • Pressure, tightness or heaviness 2%
  • Indigestion 1%
  • Sweating 1%
  • Chest pain, tightness or pressure 2%
  • Dry mouth 1%
  • Warm or cold sensation 1%
  • Sleepiness 3%
  • Tingling or prickling sensation 5%
More Zomig side effects »
How it works
almotriptanZomig
Axert (almotriptan) is a selective serotonin receptor agonist called a triptan. Migraine headaches happen when blood vessels are too open and allow too much blood in the brain. Axert (almotriptan) tightens the blood vessels which relieves the pain.Zomig (zolmitriptan) is a triptan. It prevents the enlargement of blood vessels in your brain, which causes migraines.
Type of medication
almotriptanZomig
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
almotriptanZomig
  • Pill
  • Pill
  • Dissolving tablet
  • Nasal spray
Used for
almotriptanZomig
Risk factors for serious side effects
almotriptanZomig
  • Heart disease
  • history of chest pain/angina
  • uncontrolled high blood pressure
  • History of a stroke
  • Using Axert (almotriptan) for more than 10 days a month
Detailed Axert (almotriptan) risks & warnings »
  • Heart disease
  • history of chest pain/angina
  • uncontrolled high blood pressure
  • History of a stroke
  • Using Zomig (zolmitriptan) or other migraine treatment medications for 10 or more days a month
Detailed Zomig (zolmitriptan) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
almotriptanZomig
  • You can take Axert (almotriptan) with or without food.
No food related info.
Pain
almotriptanZomig
  • Effective at relieving migraine pain.
No pain related info.
Upsides and benefits
almotriptanZomig
  • Effective at relieving migraine pain.
  • You can take Axert (almotriptan) with or without food.
  • Axert (almotriptan) works within 30 minutes of taking it, and most people don't have to take a second dose to control their pain.
  • Axert (almotriptan) is available in generic.
  • Zomig (zolmitriptan) is is a first choice treatment to treat severe migraines.
  • There are different forms of Zomig (zolmitriptan) available, including a dissolving pill and a nasal spray if you have trouble swallowing during a migraine attack.
  • The regular and dissolving pill forms of Zomig (zolmitriptan) are available as generics.
Downsides and risks
almotriptanZomig
  • Axert (almotriptan) can only treat migraines that have already started. It can't stop a migraine from happening.
  • Axert (almotriptan) is only available as a pill that must be swallowed, so taking it might be difficult for someone who has trouble swallowing during a migraine.
  • If you're taking the nasal spray form of Zomig (zolmitriptan), you have to follow the instructions exactly or you won't get the full dose of medicine.
  • The nasal spray form of Zomig (zolmitriptan) is only available as brand name, so it can be expensive.
  • If you have heart disease or history of stroke, Zomig (zolmitriptan) may not be the best choice for you. Talk to your doctor about your medical history.
Tips from our pharmacists for people taking the medication
almotriptanZomig
  • Axert (almotriptan) can only treat a migraine that's already happening. Axert (almotriptan) doesn't stop migraines from starting.
  • Take Axert (almotriptan) at the first sign of a migraine. You can take another dose if you don't feel better after 2 hours. Don't take more than two doses every 24 hours.
  • Axert (almotriptan) can make you feel dizzy or tired when you first start taking it. Don't drive or do anything that requires concentration until you know how your body reacts to it.
  • If you finish the entire month's supply of Axert (almotriptan) before your next refill or if you have more than 4 migraines a month, talk to your doctor to see if you should try something else.
  • Axert (almotriptan) can cause nausea or tightness in the chest or throat. Talk to your doctor if it bothers you.
  • Doesn't prevent migraines.
  • Use as soon as you feel a migraine starting. You can take another dose 2 hours later, but don't take more than 10 mg total in 24 hours.
  • Don't use it excessively since it can cause you to have more headaches. Talk to your doctor if you are having more than 4 migraines in a month.
Learn more
More about almotriptanSide effectsAlternativesFDA package insert
Have you used Axert (almotriptan)?
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More about ZomigSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zomig (zolmitriptan)?
Worth itNot sureNot worth it