Compare Alora vs. Estring

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Alora
(estradiol patch)

Estring
(estradiol vaginal ring)

Relieves hot flashes and vaginal dryness due to menopause and strengthens your bones. Alora (estradiol patch) treats symptoms from low estrogen, and it may have fewer side effects than oral estrogen pills.Relieves vaginal dryness due to menopause. Estring (Estradiol Vaginal Ring) is a vaginal ring that may be less of a hassle than estrogen pills, gels, patches, or vaginal creams, but comes with the same side effects.
Reviews & ratings
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Have you used Alora (estradiol patch)?
Worth itNot sureNot worth it
Reviews for Estring
63%
-13% worse vs. Alora
39%
+11% better vs. Alora
18%
-32% worse vs. Alora
Have you used Estring (estradiol vaginal ring)?
Worth itNot sureNot worth it
Side effects
AloraEstring
  • Breast pain 7%
  • Heartburn 8%
  • Stomach pain 3%
  • Weakness 3%
More Alora side effects »
  • Headache 13%
  • Leukorrhea 7%
  • Back Pain 6%
  • Genital Moniliasis 6%
  • Upper Respiratory Tract Infection 5%
  • Vaginitis 5%
  • Vaginal Discomfort/Pain 5%
  • Sinusitis 4%
  • Asymptomatic Genital Bacterial Growth 4%
  • Abdominal Pain 4%
More Estring side effects »
How it works
AloraEstring
Alora (estradiol patch) replaces an estrogen hormone that your body loses during and after menopause. Higher levels of the hormone relieve symptoms of low estrogen, menopause, and prevent bone loss.Estring (Estradiol Vaginal Ring) is a vaginal ring that replaces estrogen hormones in your vagina that your body loses during menopause. Estrogen helps rebuild and maintain vaginal tissue, relieving symptoms of vaginal dryness, soreness, irritation, and painful sex.
Type of medication
AloraEstring
Prescription onlyPrescription only
Available as
AloraEstring
  • Patch
  • Vaginal ring
Used for
AloraEstring
  • Treats Hot Flashes Night Sweats And Flushing In Women In Menopause
  • Vaginal Dryness And Inflammation
Risk factors for serious side effects
AloraEstring
  • Using estrogen for more than one year
  • Personal or family history of breast cancer
  • Personal or family history of blood clots
  • Smoking
Detailed Alora (estradiol patch) risks & warnings »
  • Using estrogen for more than one year
  • Personal or family history of breast cancer
  • Duration of use
  • Personal or family history of blood clots
  • Obesity
Detailed Estring (estradiol vaginal ring) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Weight
AloraEstring
  • Can cause nausea, dizziness, bloating, and breast tenderness.
No weight related info.
Upsides and benefits
AloraEstring
  • Alora (estradiol patch) replaces estrogen to your whole body and relieves many symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • The patch is good for people who don't want to or can't take daily pills.
  • Can be worn while swimming, bathing, and showering.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy.
  • Estring (Estradiol Vaginal Ring) relieves vaginal dryness and irritation to make sex more enjoyable.
  • Works locally in the vagina and doesn't expose the rest of your body to estrogen like pills do.
  • Good option for people who don't want to take oral pills.
  • Generally works well with fewer side effects.
  • Many women think Estring (Estradiol Vaginal Ring) is easy to insert and comfortable to use.
  • In a 12-week study, Estring (Estradiol Vaginal Ring) worked well to improve vaginal problems, reduced pain during urination, and sudden urges to urinate.
  • Estring (Estradiol Vaginal Ring) slowly releases estrogen over the 90 days the ring is in place, so you only have to remove and insert a new one every three months.
Downsides and risks
AloraEstring
  • You need to replace Alora (estradiol patch) twice a week, compared to other patches that are once a week.
  • Patches can fall off.
  • Increases your risk of uterine and breast cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
  • Can't be used in people with liver problems.
  • Estring (Estradiol Vaginal Ring) may not be the best estrogen product if you have a narrow vagina or frequent vaginal infections.
  • The ring can fall out without you noticing it.
  • Increases your risk of endometrial (uterine cancer).
  • If you have your uterus, you might need to use Estring (Estradiol Vaginal Ring) with another hormone called progestin to lower your risk of uterine cancer.
  • Can be expensive since it's only available as a brand name product.
Tips from our pharmacists for people taking the medication
AloraEstring
  • Remove the patch by tearing the package by hand and not with scissors. Never cut the patch.
  • Apply the sticky side of the patch to clean, dry, hairless skin below your belly button on areas as instructed by the manufacturer (never on your breast).
  • Replace the patch twice a week (every 3-4 days) on a different area of the skin to lower the risk of skin irritation.
  • Fold together the sticky sides of used patches before throwing them away to prevent exposing others to the medicine. Don't flush them down the toilet.
  • Can cause nausea, dizziness, bloating, and breast tenderness.
  • Tell your doctor about any unusual vaginal bleeding.
  • Insert the ring as deeply as possible into your vagina. You shouldn't feel the ring once it's inserted.
  • The ring is good for 90 days in your vagina. If it falls out before the 90 days are up, just clean it with warm water and reinsert.
  • You don’t have to remove Estring (Estradiol Vaginal Ring) to treat a vaginal infection or have sex.
  • It can take up to 2 to 3 weeks to feel the full benefits.
  • Most people don't have many side effects, but temporary nausea, dizziness, bloating, and breast tenderness are possible.
  • Tell your doctor about any unusual vaginal bleeding.
Learn more
More about AloraSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Alora (estradiol patch)?
Worth itNot sureNot worth it
More about EstringSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Estring (estradiol vaginal ring)?
Worth itNot sureNot worth it