Compare Altace vs. Avapro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Altace
(ramipril)

Avapro
(irbesartan)

Lowers blood pressure. Altace (ramipril) is a good blood pressure-lowering medicine that protects your kidney function. It's also a good option if you have trouble swallowing pills since you can open the capsules.Lowers blood pressure. Avapro (irbesartan) is a good blood pressure-lowering medicine that protects your kidneys and has few side effects.
Reviews & ratings
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Have you used Altace (ramipril)?
Worth itNot sureNot worth it

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Have you used Avapro (irbesartan)?
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Side effects
AltaceAvapro
  • Nausea 1%
  • Low blood pressure when standing up 1%
  • Fainting 1%
  • Vomiting 1%
  • Vertigo 1%
  • Chest pain 1%
  • Dizziness 1%
  • Increased cough 4%
  • Low blood pressure 6%
More Altace side effects »
  • Heartburn 1%
  • Diarrhea 1%
  • Fatigue 1%
More Avapro side effects »
How it works
AltaceAvapro
Altace (ramipril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that usually tightens blood vessels. By making blood vessels relax, it lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Avapro (irbesartan) is an angiotensin receptor blocker (ARB). It lowers blood pressure by blocking a chemical that tightens the blood vessels. This allows more blood and oxygen to get to your heart and other organs.
Type of medication
AltaceAvapro
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
AltaceAvapro
  • Pill
  • Pill
Used for
AltaceAvapro
Risk factors for serious side effects
AltaceAvapro
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Using salt substitutes
Detailed Altace (ramipril) risks & warnings »
  • Women of childbearing age
  • History of kidney problems
  • African descent
  • Current kidney problems
  • Using medicines that increase potassium
Detailed Avapro (irbesartan) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
AltaceAvapro
  • Requires routine blood tests to check how your kidneys are working.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Avapro (irbesartan) can hurt your kidneys. If you already have kidney damage, Avapro (irbesartan) could make it worse. Your doctor will do regular blood tests to check your kidneys, usually before you start Avapro (irbesartan), and at least once a year while you're still on it.
  • You'll need to have blood tests done regularly since Avapro (irbesartan) can affect your kidneys and potassium levels.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Upsides and benefits
AltaceAvapro
  • Altace (ramipril) is a first-choice blood pressure treatment for many people.
  • It lowers your risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Altace (ramipril) is the only ACE inhibitor that you can open and sprinkle in applesauce or water.
  • Avapro (irbesartan) lowers your risk of heart attack and stroke.
  • It works similar to ACE inhibitors (like lisinopril), but it doesn't have the same side effects like coughing and facial swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for people with heart failure since it lowers the risk of death and further damage to your heart.
  • Available in generic, and available with hydrochlorothiazide as a combination tablet.
Downsides and risks
AltaceAvapro
  • Some people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • You'll need to get routine blood tests to see how this medicine is affecting your body.
  • Women, be sure to use contraception while taking this medication since it can harm a fetus. It's also not safe to use if you're already pregnant.
  • You'll need to get yearly blood tests while taking Avapro (irbesartan) to see how it is affecting your body.
  • It's not safe to use Avapro (irbesartan) if you're pregnant.
  • Avapro (irbesartan) can cause the level of potassium in your blood to go up.
  • You'll need to get medical help if you notice any unusual swelling around your head and neck.
  • Can't be used in children under 18.
Tips from our pharmacists for people taking the medication
AltaceAvapro
  • Altace (ramipril) can make you feel dizzy for the first few days.
  • Check your blood pressure one week after starting Altace (ramipril) or changing your dose.
  • Tell your doctor about any dizziness, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check how your kidneys are working.
  • Don't take Altace (ramipril) if you're pregnant.
  • If you can't swallow the capsule, you can open it up and mix with water, apple juice, or apple sauce.
  • Avapro (irbesartan) can make you feel a little dizzy for the first few days.
  • You'll need to have blood tests done regularly since Avapro (irbesartan) can affect your kidneys and potassium levels.
  • Don't eat a lot of foods that are high in potassium or use salt substitutes that contain potassium.
  • Tell your doctor about any dizziness or muscle weakness that doesn't go away after the first few days.
  • Don't take Avapro (irbesartan) if you're pregnant.
Learn more
More about AltaceSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Altace (ramipril)?
Worth itNot sureNot worth it
More about AvaproSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Avapro (irbesartan)?
Worth itNot sureNot worth it