Compare Altace vs. Losartan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Altace
(Ramipril)

Cozaar
(Losartan)

Lowers blood pressure. Altace (Ramipril) is a good blood pressure-lowering medicine that protects kidney function. Easy to use if you can't swallow whole capsules.Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.
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Reviews & ratings
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Reviews for Cozaar (Losartan)
57%
+17% vs. Altace (Ramipril)
47%
+7% vs. Altace (Ramipril)
16%
+24% vs. Altace (Ramipril)
Side effects
AltaceLosartan
  • Low blood pressure 6%
  • Cough 5%
  • Cough increased 4%
  • Dizziness 1%
  • Nausea 1%
  • Fainting 1%
  • Positional low blood pressure 1%
  • Fatigue 1%
  • Vomiting 1%
  • Vertigo 1%
More Altace side effects »
  • Urinary tract infection 6%
  • Diarrhea 5%
  • Low blood sugar 4%
  • Low blood pressure 4%
  • Muscle weakness/fatiguea/fatigue 4%
  • Hyperkalemia 4%
  • Chest pain 4%
  • Low red blood cells 3%
  • Muscular weakness 3%
  • Orthostatic hypotension 3%
More Losartan side effects »
How it works
AltaceLosartan
Altace (Ramipril) is an angiotensin converting enzyme (ACE) inhibitor. By blocking a chemical that usually tightens blood vessels, it makes blood vessels relax. This lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
AltaceLosartan
Antihypertensive
ACE inhibitor
Prescription only
Antihypertensive
Angiotensin receptor blocker
Prescription only
Available as
AltaceLosartan
  • Pill
  • Pill
Used for (click to learn more)
AltaceLosartan
Risk factors for serious side effects
AltaceLosartan
  • Women of childbearing age
  • History of ACE inhibitor induced cough
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
  • History of kidney problems
Detailed Altace (Ramipril) risks & warnings »
  • Women of childbearing age
  • Concurrent liver disease
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Cozaar (Losartan) risks & warnings »
Pregnancy category
AltaceLosartan
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
DFDA pregnancy category (Weigh risks vs. benefits)

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check how your kidneys are working.
  • Altace (Ramipril) has a risk of making your kidneys not work as well. It's important to get blood work done to check your kidney function before starting Altace (Ramipril) and at least yearly after.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
AltaceLosartan
  • The only ACE inhibitor that comes in a capsule that you can sprinkle in applesauce or water.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides and risks
AltaceLosartan
  • Up to 1 and 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
Tips from our pharmacists for people taking the medication
AltaceLosartan
  • Check your blood pressure one week after starting this medication, and tell your doctor if it hasn't improved.
  • Requires routine blood tests to check how your kidneys are working.
  • Don't take if you are pregnant.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Can cause dizziness in the first few days.
Learn more
More about AltaceSide effectsReviews & ratingsAlternativesFDA package insert
More about LosartanSide effectsReviews & ratingsAlternativesFDA package insert