Compare Altace vs. Losartan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Altace
(ramipril)

Cozaar
(losartan)

Lowers blood pressure. Altace (ramipril) is a good blood pressure-lowering medicine that protects your kidney function. It's also a good option if you have trouble swallowing pills since you can open the capsules.Lowers blood pressure. Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.
Reviews & ratings
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Have you used Altace (ramipril)?
Worth itNot sureNot worth it
Reviews for Losartan
57%
-7% worse vs. Altace
48%
-6% worse vs. Altace
16%
-17% worse vs. Altace
535 reviews
Have you used Cozaar (losartan)?
Worth itNot sureNot worth it
Side effects
AltaceLosartan
  • Low blood pressure 6%
  • Increased cough 4%
  • Dizziness 1%
  • Chest pain 1%
  • Nausea 1%
  • Low blood pressure when standing up 1%
  • Fainting 1%
  • Vomiting 1%
  • Vertigo 1%
More Altace side effects »
  • Upper respiratory infection 1%
  • Dizziness 1%
  • Back pain 1%
  • Nasal congestion 1%
  • Urinary tract infection 6%
  • Diarrhea 5%
  • Asthenia/Fatigue 4%
  • Anemia 3%
  • Hypoglycemia 4%
  • Back pain 2%
More Losartan side effects »
How it works
AltaceLosartan
Altace (ramipril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that usually tightens blood vessels. By making blood vessels relax, it lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Cozaar (Losartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
AltaceLosartan
Prescription onlyPrescription only
Available as
AltaceLosartan
  • Pill
  • Pill
Used for
AltaceLosartan
Risk factors for serious side effects
AltaceLosartan
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicines that increase potassium
  • Using salt substitutes
Detailed Altace (ramipril) risks & warnings »
  • Women of childbearing age
  • Concurrent liver disease
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Cozaar (losartan) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
AltaceLosartan
  • Requires routine blood tests to check how your kidneys are working.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Upsides and benefits
AltaceLosartan
  • Altace (ramipril) is a first-choice blood pressure treatment for many people.
  • It lowers your risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Altace (ramipril) is the only ACE inhibitor that you can open and sprinkle in applesauce or water.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides and risks
AltaceLosartan
  • Some people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • You'll need to get routine blood tests to see how this medicine is affecting your body.
  • Women, be sure to use contraception while taking this medication since it can harm a fetus. It's also not safe to use if you're already pregnant.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
Tips from our pharmacists for people taking the medication
AltaceLosartan
  • Altace (ramipril) can make you feel dizzy for the first few days.
  • Check your blood pressure one week after starting Altace (ramipril) or changing your dose.
  • Tell your doctor about any dizziness, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check how your kidneys are working.
  • Don't take Altace (ramipril) if you're pregnant.
  • If you can't swallow the capsule, you can open it up and mix with water, apple juice, or apple sauce.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
Learn more
More about AltaceSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Altace (ramipril)?
Worth itNot sureNot worth it
More about LosartanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Cozaar (losartan)?
Worth itNot sureNot worth it