Compare Amaryl vs. Janumet
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Amaryl (glimepiride) is an effective medicine for lowering blood sugar, but it can cause weight gain.
Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.
- Needs to be taken only once a day.
- Effectively lowers blood sugar and A1c levels by 1-2%. (A1c is a test that measures your average blood sugars over the past 3 months).
- Amaryl (glimepiride) is an oral medicine so it might be a good alternative for those who don't like injections.
- Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
- Available as a generic form and is relatively cheap.
- This 2-in-1 combination can lower the number of pills you have to take daily.
- Lowers A1c (average blood sugar over time) up to 2.5%.
- Available in extended and immediate release forms to allow better control of your blood sugar.
- Doesn't increase your appetite unlike other anti-diabetic medicines.
- Does not cause hypoglycemia or very low blood sugar.
- Amaryl (glimepiride) might cause weight gain.
- Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
- Not preferred for people age 65 or older because they are at higher risk of experiencing side effects such as low blood sugar.
- Might lose its effectiveness over time.
- Needs to be taken 30 minutes before a meal for it to be most effective.
- Available as brand name only and may be expensive.
- Metformin component usually causes upset stomach.
- Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
- Not appropriate for those with poor kidney function.
- Extended release
- Accidental injury6%
- Flu syndrome5%
- Low blood sugar
Skipping meals or having inconsistent meal times
...and 4 more risk factors
- Severe allergic reaction
History of allergy to sulfa-containing medicine
- Breakdown of red blood cells
People with G6PD deficiency
- Kidney and liver disease
Those with kidney and/or liver disease
- Excess lactic acid in the blood
...and 5 more risk factors