Compare Ambien vs. Anafranil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ambien (zolpidem)

Prescription only

Anafranil (Clomipramine)

Prescription only
Helps you sleep.

Ambien (zolpidem) aids in falling asleep and staying asleep, but it can be habit-forming and might be more likely than other sleep medicines to cause side effects.

3.7/ 5 average rating with 1375 reviewsforAmbien
Helps with your actions.

Anafranil (Clomipramine) is helpful in treating OCD, but it can have a lot of side effects.

Upsides
  • Effective at helping people fall asleep faster and sleep longer.
  • Extended release form is particularly good for staying asleep, and you can use it for longer than the immediate release form.
  • Generic is available.
  • Works well to decrease the symptoms of obsessive-compulsive disorder (OCD).
  • Helps some people see improvements in their mood.
  • Can help you sleep.
  • Lower risk of causing heart problems compared to other medicine in this class.
Downsides
  • Not typically used for long-term treatment because it can be habit-forming.
  • Some people find that Ambien (zolpidem) becomes less effective over time.
  • More likely to cause sleep-walking, sleep-driving, and sleep-eating.
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
  • It's more likely to cause side effects like dizziness, drowsiness, weight gain, and constipation compared to other medicines in this class.
  • Can cause sexual performance problems in men.
  • Increases the risk of falls, especially when used in the elderly.
Used for
Dosage forms
  • Pill
  • Oral spray
  • Sublingual pill
  • Pill
Price
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Reviews
1375 reviews so far
67%
saidit'sworth it
50%
saiditworked well
16%
saidit'sa big hassle

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Side effects
18possible side effects
  • Drowsiness
    8%
  • Headache
    7%
  • Dizziness
    5%
  • Allergic reactions
    4%
  • Sinus infection
    4%
  • Dry mouth
    3%
  • Back pain
    3%
  • Lack of energy
    3%
  • Drugged feeling
    3%
  • Diarrhea
    3%
  • Sore throat
    3%
  • Flu-like symptoms
    2%
  • Racing heart
    2%
  • Lightheadedness
    2%
  • Depression
    2%
  • Abdominal pain
    2%
  • Constipation
    2%
  • Rash
    2%
See more detailed side effects
109possible side effects
  • Dry mouth
    84%
  • Somnolence
    54%
  • Tremor
    54%
  • Dizziness
    54%
  • Headache
    52%
  • Constipation
    47%
  • Ejaculation failure
    42%
  • Fatigue
    39%
  • Nausea
    33%
  • Increased sweating
    28%
  • Insomnia
    25%
  • Dyspepsia
    22%
  • Anorexia
    22%
  • Libido change
    21%
  • Any side effect
    20%
  • Impotence
    20%
  • Nervousness
    18%
  • Weight increase
    18%
  • Abnormal vision
    18%
  • Pharyngitis
    14%
  • Micturition disorder
    14%
  • Myoclonus
    13%
  • Diarrhea
    13%
  • Myalgia
    13%
  • Abdominal pain
    13%
  • Rhinitis
    12%
  • Dysmenorrhea
    12%
  • Increased appetite
    11%
  • Digestive system complaints, mainly nausea and vomiting
    10%
  • Paresthesia
    9%
  • Memory impairment
    9%
  • Anxiety
    9%
  • Sleep disorder
    9%
  • Rash
    8%
  • Flushing
    8%
  • Taste perversion
    8%
  • Twitching
    7%
  • Vomiting
    7%
  • Chest pain
    7%
  • Allergy
    7%
  • Weight decrease
    7%
  • Bronchospasm
    7%
  • Urinary retention
    7%
  • Pruritus
    6%
  • Flatulence
    6%
  • Postural hypotension
    6%
  • Sinusitis
    6%
  • Coughing
    6%
  • Urinary tract infection
    6%
  • Tinnitus
    6%
  • Back pain
    6%
  • Nervous system complaints, mainly somnolence
    5%
  • Impaired concentration
    5%
  • Depression
    5%
  • Tooth disorder
    5%
  • Hot flushes
    5%
  • Micturition frequency
    5%
  • Hypertonia
    4%
  • Fever
    4%
  • Palpitation
    4%
  • Tachycardia
    4%
  • Lactation (nonpuerperal)
    4%
  • Menstrual disorder
    4%
  • Pain
    4%
  • Otitis media
    4%
  • Psychosomatic disorder
    3%
  • Yawning
    3%
  • Confusion
    3%
  • Speech disorder
    3%
  • Abnormal dreaming
    3%
  • Agitation
    3%
  • Migraine
    3%
  • Abnormal lacrimation
    3%
  • Arthralgia
    3%
  • Depersonalization
    2%
  • Irritability
    2%
  • Emotional lability
    2%
  • Dermatitis
    2%
  • Acne
    2%
  • Dry skin
    2%
  • Gastrointestinal disorder
    2%
  • Dysphagia
    2%
  • Local edema
    2%
  • Chills
    2%
  • Epistaxis
    2%
  • Dysuria
    2%
  • Cystitis
    2%
  • Vaginitis
    2%
  • Leukorrhea
    2%
  • Breast enlargement
    2%
  • Mydriasis
    2%
  • Thirst
    2%
  • Panic reaction
    2%
  • Aggressive reaction
    2%
  • Paresis
    2%
  • Abnormal skin odor
    2%
  • Eructation
    2%
  • Ulcerative stomatitis
    2%
  • Asthenia
    2%
  • Halitosis
    2%
  • Syncope
    2%
  • Dyspnea
    2%
  • Laryngitis
    2%
  • Anisocoria
    2%
  • Blepharospasm
    2%
  • Ocular allergy
    2%
  • Vestibular disorder
    2%
  • Muscle weakness
    2%
  • Anemia
    2%
See more detailed side effects
Risks and risk factors
  • Dependence and withdrawal
    • Continuous use of Ambien (zolpidem) for 2 weeks or more
  • Driving impairment
    • Alcohol
    • Taking other medications that make you less alert
    • Less than 8 hours of sleep.
  • Abnormal thoughts
    • Undiagnosed psychiatric conditions
  • Performing activities while asleep
    • Taking Ambien (zolpidem) with alcohol or drugs that cause drowsiness
  • Risk of falls and injury
    • Higher dose
    • Liver problems
    • Taking Ambien (zolpidem) with other nervous system depressants
    • Long-term use
    • Elderly (70 years or older)
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Seizure
    • History of seizure
    • Taking other medicines that increase seizure risk
    • Alcoholism
  • Withdrawal
    • Stopping Anafranil (Clomipramine) suddenly
  • Low blood pressure
    • Age 65 years or older
  • Heart problems
    • History of heart disease
    • Older age
    • Electrolyte imbalance
See more detailed risks and warnings