Compare Ambien vs. Butisol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ambien
(zolpidem)

Butisol
(butabarbital)

Helps you sleep. Ambien (Zolpidem) is good for falling asleep and staying asleep, but it can be habit-forming and might be more likely than other sleep medicines to cause disturbing side effects.Helps you fall asleep. Butisol (butabarbital) is not very good for sleeping problems because it can be addictive.
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Coupons for Ambien
Best available price for 30 (10mg) tablets of zolpidem
Coupons for Butisol
Best available price for 30 (30mg) tablets of butabarbital
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.1Ambien
Reviews for Ambien (zolpidem)
67%
of people (All ages) say Ambien (zolpidem) is worth it
50%
say it works well
16%
say it's a big hassle
1375 reviews
Have you used Ambien (zolpidem)?
Worth itNot sureNot worth it
Reviews for Butisol (butabarbital)
Not enough review data. Review it!
-67% worse vs. Ambien (zolpidem)
Not enough review data. Review it!
-50% worse vs. Ambien (zolpidem)
Not enough review data. Review it!
-84% worse vs. Ambien (zolpidem)
Have you used Butisol (butabarbital)?
Worth itNot sureNot worth it
Side effects
AmbienButisol
  • Drowsiness 3%
  • Dizziness 4%
  • Sinus inflammation 2%
  • Allergy 3%
  • Drugged feeling 3%
  • Back pain 1%
  • Sore throat 2%
  • Lack of energy 2%
  • Dry mouth 2%
  • Diarrhea 1%
More Ambien side effects »
  • Sleepiness 3%
More Butisol side effects »
How it works
AmbienButisol
Ambien (Zolpidem) is in a class of drugs called sedative-hypnotics. Researchers don't know exactly how it works, but it interacts with your brain to make you relaxed and sleepy.Butisol (butabarbital) is a barbiturate. It works by calming and relaxing you so you're able to sleep.
Type of medication
AmbienButisol
Prescription only
Prescription only
Available as
AmbienButisol
  • Pill
  • Extended release
  • Pill
Used for
AmbienButisol
Risk factors for serious side effects
AmbienButisol
  • Continuous use for 2 weeks or more
  • Alcohol
  • Taking other medicines that make you less alert
  • Less than 7 hours of sleep
  • Undiagnosed psychiatric conditions
Detailed Ambien (zolpidem) risks & warnings »
  • Having acute or chronic pain
  • age 65 or older
  • Drinking alcohol
  • Taking narcotics, tranquilizers or antihistamines
Detailed Butisol (butabarbital) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
AmbienButisol
No interactions related info.
  • Butisol (butabarbital) can interact with a lot of medicines, vitamins and supplements.
Alcohol
AmbienButisol
  • Avoid alcohol and drugs.
  • Don't drink alcohol or take narcotics with Butisol (butabarbital) since this can slow your breathing.
  • Don't drink alcohol or take narcotics, tranquilizers or antihistamines if you're taking Butisol (butabarbital). This can slow down your breathing. Talk to your doctor about other options to help you sleep.
Kidneys and liver
AmbienButisol
  • Might not be safe if you have problems with your liver, kidneys, or lungs, or if you have a history of depression.
No kidneys and liver related info.
Pain
AmbienButisol
No pain related info.
  • If you're having acute or chronic pain, or if you're older, Butisol (butabarbital) can cause you to feel more awake instead of sleepy, or you may not notice changes in your pain until it wears off. Talk to your doctor about other options to help you sleep if this happens.
Sleep
AmbienButisol
  • Effective at helping people fall asleep faster and sleep longer.
  • Only take it if you have time to sleep for at least 7 hours.
  • Can cause headache, drowsiness, and dizziness.
  • Ambien (Zolpidem) make you feel drowsy and sleepy, leading to falls and severe injuries. This is especially a risk if your older. Falls from sleep medicines like Ambien (Zolpidem) have caused severe injuries such as hip fractures and head injury. You may need a lower dose if you're taking other medicine that affects your nervous system or have issues with falls in the past. Check with your doctor first.
No sleep related info.
Upsides and benefits
AmbienButisol
  • Effective at helping people fall asleep faster and sleep longer.
  • Extended release form is particularly good for staying asleep, and you can use it for longer than the immediate release form.
  • Butisol (butabarbital) works very quickly to help you fall asleep, within 45-60 minutes, and it lasts 6-8 hours.
Downsides and risks
AmbienButisol
  • Not typically used for long-term treatment because it can be habit-forming.
  • Some people find that it's less effective over time.
  • More likely to cause sleep-walking, sleep-driving, and sleep-eating.
  • Might not be safe if you have problems with your liver, kidneys, or lungs, or if you have a history of depression.
  • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behavior so that you can sleep better naturally.
  • Your body can get used to needing Butisol (butabarbital) for sleeping.
  • Butisol (butabarbital) can interact with a lot of medicines, vitamins and supplements.
Tips from our pharmacists for people taking the medication
AmbienButisol
  • Take 30 to 45 minutes before bedtime.
  • Only take it if you have time to sleep for at least 7 hours.
  • Very addictive. Meant for short-term treatment. Dependence can form after daily use for 2 weeks.
  • Can cause headache, drowsiness, and dizziness.
  • Can cause sleep-walking, sleep-driving, and sleep-eating.
  • Works best if taken without food.
  • Avoid alcohol and drugs.
  • Withdrawal symptoms usually resolve in 1 to 2 nights.
  • Report any confusion or changes in thoughts or behavior.
  • Don't use Butisol (butabarbital) for more than 2 weeks, since it doesn't work as well after that.
  • Don't stop Butisol (butabarbital) suddenly, especially if you've been taking it for a while. Talk to your doctor about how to get off it safely.
  • Don't drink alcohol or take narcotics with Butisol (butabarbital) since this can slow your breathing.
  • Butisol (butabarbital) can make your birth control less effective. You should use condoms or diaphragms while taking it.
  • Talk to your doctor if Butisol (butabarbital) doesn't help you sleep better after taking it for 7 days.
Learn more
More about AmbienSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Ambien (zolpidem)?
Worth itNot sureNot worth it
More about ButisolSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Butisol (butabarbital)?
Worth itNot sureNot worth it