Compare Ambien vs. Rozerem

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ambien
(Zolpidem)

Rozerem
(Ramelteon)

Helps you sleep. Ambien (Zolpidem) is good for falling asleep and staying asleep, but it can be habit-forming and might be more likely than other sleep medicines to cause disturbing side effects.Coming soon.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.1Ambien
Reviews for Ambien (Zolpidem)
67%
of people (All ages) say Ambien (Zolpidem) is worth it
50%
say it works well
16%
say it's a big hassle
1375 reviews
Have you used Ambien (Zolpidem)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Rozerem (Ramelteon)?
Worth itNot sureNot worth it
Side effects
AmbienRozerem
  • Drowsiness 3%
  • Dizziness 4%
  • Sinus inflammation 2%
  • Allergy 3%
  • Drugged feeling 3%
  • Back pain 1%
  • Sore throat 2%
  • Lack of energy 2%
  • Dry mouth 2%
  • Diarrhea 1%
More Ambien side effects »

We haven’t found good data for Rozerem side effects.

FDA side effect reports for Rozerem »
How it works
AmbienRozerem
Ambien (Zolpidem) is in a class of drugs called sedative-hypnotics. Researchers don't know exactly how it works, but it interacts with your brain to make you relaxed and sleepy.Coming soon.
Type of medication
AmbienRozerem
Prescription only
Available as
AmbienRozerem
  • Pill
  • Extended release
  • Pill
Used for
AmbienRozerem
  • Insomnia
Risk factors for serious side effects
AmbienRozerem
  • Continuous use for 2 weeks or more
  • Alcohol
  • Taking other medicines that make you less alert
  • Less than 7 hours of sleep
  • Undiagnosed psychiatric conditions
  • Taking with alcohol or drugs
    • Respiratory conditions
    • Liver problems
    • Muscle disease
    • Elderly
    • Higher dose
    • Liver problems
    • Taking Ambien (Zolpidem) with other nervous system depressants
    • Long-term use
    • Women of childbearing age
    • Breast-feeding
    Detailed Ambien (Zolpidem) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    AmbienRozerem
    • Avoid alcohol and drugs.
    No alcohol related info.
    Kidneys and liver
    AmbienRozerem
    • Might not be safe if you have problems with your liver, kidneys, or lungs, or if you have a history of depression.
    No kidneys and liver related info.
    Sleep
    AmbienRozerem
    • Effective at helping people fall asleep faster and sleep longer.
    • Only take it if you have time to sleep for at least 7 hours.
    • Can cause headache, drowsiness, and dizziness.
    • Ambien (Zolpidem) make you feel drowsy and sleepy, leading to falls and severe injuries. This is especially a risk if your older. Falls from sleep medicines like Ambien (Zolpidem) have caused severe injuries such as hip fractures and head injury. You may need a lower dose if you're taking other medicine that affects your nervous system or have issues with falls in the past. Check with your doctor first.
    No sleep related info.
    Upsides and benefits
    AmbienRozerem
    • Effective at helping people fall asleep faster and sleep longer.
    • Extended release form is particularly good for staying asleep, and you can use it for longer than the immediate release form.
    Coming soon
    Downsides and risks
    AmbienRozerem
    • Not typically used for long-term treatment because it can be habit-forming.
    • Some people find that it's less effective over time.
    • More likely to cause sleep-walking, sleep-driving, and sleep-eating.
    • Might not be safe if you have problems with your liver, kidneys, or lungs, or if you have a history of depression.
    • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behavior so that you can sleep better naturally.
    Coming soon
    Tips from our pharmacists for people taking the medication
    AmbienRozerem
    • Take 30 to 45 minutes before bedtime.
    • Only take it if you have time to sleep for at least 7 hours.
    • Very addictive. Meant for short-term treatment. Dependence can form after daily use for 2 weeks.
    • Can cause headache, drowsiness, and dizziness.
    • Can cause sleep-walking, sleep-driving, and sleep-eating.
    • Works best if taken without food.
    • Avoid alcohol and drugs.
    • Withdrawal symptoms usually resolve in 1 to 2 nights.
    • Report any confusion or changes in thoughts or behavior.
    Coming soon
    Learn more
    More about AmbienSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Ambien (Zolpidem)?
    Worth itNot sureNot worth it
    More about RozeremSide effectsFDA package insert
    Have you used Rozerem (Ramelteon)?
    Worth itNot sureNot worth it