Compare Ambien vs. Rozerem

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Ambien (zolpidem)

Prescription only

Rozerem (ramelteon)

Prescription only
Helps you sleep.

Ambien (zolpidem) aids in falling asleep and staying asleep, but it can be habit-forming and might be more likely than other sleep medicines to cause side effects.

3.7/ 5 average rating with 1375 reviewsforAmbien
Helps you fall asleep.

Rozerem (ramelteon) is a good sleep medicine that's not addictive, but it can be expensive.

Upsides
  • Effective at helping people fall asleep faster and sleep longer.
  • Extended release form is particularly good for staying asleep, and you can use it for longer than the immediate release form.
  • Generic is available.
  • Rozerem (ramelteon) isn't a controlled medicine, and it's safe to use in people age 65 or older.
  • If you stop taking Rozerem (ramelteon) suddenly, your insomnia won't come back.
  • Rozerem (ramelteon) won't make you feel hungover or groggy the next day.
Downsides
  • Not typically used for long-term treatment because it can be habit-forming.
  • Some people find that Ambien (zolpidem) becomes less effective over time.
  • More likely to cause sleep-walking, sleep-driving, and sleep-eating.
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
  • Rozerem (ramelteon) is only available as a brand name.
  • Rozerem (ramelteon) is only available in 1 strength.
  • If you take Rozerem (ramelteon) on a full stomach, it won't work as well.
  • Not recommended for children.
  • Rozerem (ramelteon) can't be used if you have sleep apnea.
Used for
Dosage forms
  • Pill
  • Oral spray
  • Sublingual pill
  • Pill
Price
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Reviews
1375 reviews so far
67%
saidit'sworth it
50%
saiditworked well
16%
saidit'sa big hassle

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Side effects
18possible side effects
  • Drowsiness
    8%
  • Headache
    7%
  • Dizziness
    5%
  • Allergic reactions
    4%
  • Sinus infection
    4%
  • Dry mouth
    3%
  • Back pain
    3%
  • Lack of energy
    3%
  • Drugged feeling
    3%
  • Diarrhea
    3%
  • Sore throat
    3%
  • Flu-like symptoms
    2%
  • Racing heart
    2%
  • Lightheadedness
    2%
  • Depression
    2%
  • Abdominal pain
    2%
  • Constipation
    2%
  • Rash
    2%
See more detailed side effects
5possible side effects
  • Dizziness
    4%
  • Sleepiness
    3%
  • Fatigue
    3%
  • Nausea
    3%
  • Worsening insomnia
    3%
See more detailed side effects
Risks and risk factors
  • Dependence and withdrawal
    • Continuous use of Ambien (zolpidem) for 2 weeks or more
  • Driving impairment
    • Alcohol
    • Taking other medications that make you less alert
    • Less than 8 hours of sleep.
  • Abnormal thoughts
    • Undiagnosed psychiatric conditions
  • Performing activities while asleep
    • Taking Ambien (zolpidem) with alcohol or drugs that cause drowsiness
  • Risk of falls and injury
    • Higher dose
    • Liver problems
    • Taking Ambien (zolpidem) with other nervous system depressants
    • Long-term use
    • Elderly (70 years or older)
See more detailed risks and warnings
  • Severe allergic reaction
  • Behavior changes
  • Sleepiness
  • Breathing problems
    • Alcohol
    • Taking narcotics, tranquilizers, or antihistamines
  • Hormonal changes
See more detailed risks and warnings