Compare Amerge vs. Cafergot

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Amerge (naratriptan)

Prescription only
Treats migraine headaches.

Amerge (naratriptan) isn't as good as other similar medications for migraines, but can be good if other drugs haven't worked for you.

Treats migraine headaches.

Cafergot (ergotamine / caffeine) can treat migraines, but you're more likely to have side effects.

Upsides
  • Amerge (naratriptan) is a good alternative to other triptans since it's less likely to cause side effects and if other triptans haven't worked for you.
  • Available as a generic, which makes it cheaper than other medicines and is more likely to be covered by insurances.
  • Amerge (naratriptan) comes in two different strengths.
  • Cafergot (ergotamine / caffeine) works better than other medicines if your migraines usually last more than 2 days or if you have more frequent migraines.
Downsides
  • Amerge (naratriptan) is only available as a pill that must be swallowed, so it might not be good if you have trouble swallowing when you have a migraine.
  • Unlike other migraine medications, you have to wait for 4 hours before you can take the second dose of Amerge (naratriptan).
  • Amerge (naratriptan) is not as good as other medications for treating nausea that can happen with migraines.
  • Cafergot (ergotamine / caffeine) can't stop migraines from happening. They can only treat them.
  • Cafergot (ergotamine / caffeine) can only be used for migraines. It doesn't work for other types of headaches.
  • Smoking or using products that contain nicotine can make Cafergot (ergotamine / caffeine) less effective.
Used for
Dosage forms
  • Pill
  • Pill
  • Suppository
Price
Lowest price near you
$26.03
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Lowest price near you
$653.26
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Reviews
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Side effects
6possible side effects
  • Stomach problems
    6%
  • Nausea
    4%
  • Nervous system issues
    4%
  • Unusual sensation
    2%
  • Fatigue or uneasiness
    2%
  • Pain and pressure sensation
    2%
See more detailed side effects
The Cafergot (ergotamine / caffeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Heart attack

    Heart disease

    ...and 2 more risk factors

  • Stroke

    History of a stroke

  • Medication overuse headache

    Using Amerge (naratriptan) for more than 10 days a month

  • Serotonin syndrome

    Tricyclic antidepressants

    ...and 5 more risk factors

  • Increased blood pressure

    Uncontrolled high blood pressure

  • Blood vessel issues

    High blood pressure

    ...and 2 more risk factors

See more detailed risks and warnings
  • Heart and circulation problems

    Overdosing Cafergot (ergotamine / caffeine)

    ...and 1 more risk factors

  • Dependency and withdrawal

    Taking Cafergot (ergotamine / caffeine) regularly for months

See more detailed risks and warnings