Compare Amerge vs. ergotamine

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Treats migraine headaches. Amerge (naratriptan) isn't as good as other similar medications for migraines, but can be good if other drugs haven't worked for you.Treats migraine headaches. Ergomar (ergotamine) has more side effects than other medicines used to treat migraines.
Reviews & ratings
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Have you used Amerge (naratriptan)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Ergomar (ergotamine)?
Worth itNot sureNot worth it
Side effects
  • Stomach problems 1%
  • Nervous system issues 1%
  • Unusual sensation 1%
  • Fatigue or uneasiness 1%
  • Tingling or prickling sensation 2%
  • Dizziness 1%
  • Drowsiness 2%
  • Pain & pressure in throat or neck 1%
More Amerge side effects »

The ergotamine FDA package insert doesn’t have numbers about how common side effects are.

More about ergotamine side effects »
How it works
Amerge (naratriptan) is a selective serotonin receptor agonist or triptan. Migraine headaches happen when blood vessels are too open and allow too much blood in the brain. Amerge (naratriptan) tightens the blood vessels which relieves the pain.Ergomar (ergotamine) is an ergot alkaloid. It tightens the blood vessels in your brain to relieve the pain of your headaches.
Type of medication
Prescription onlyPrescription only
Available as
  • Pill
  • Dissolving pill
Used for
Risk factors for serious side effects
  • Heart disease
  • history of chest pain/angina
  • uncontrolled high blood pressure
  • History of a stroke
  • Using Amerge (naratriptan) for more than 10 days a month
Detailed Amerge (naratriptan) risks & warnings »
  • Macrolide antibiotics
  • Protease inhibitors
  • Taking Ergomar (ergotamine) more than the recommended amount daily or weekly
  • Taking Ergomar (ergotamine) regularly for months
Detailed Ergomar (ergotamine) risks & warnings »

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Upsides and benefits
  • Amerge (naratriptan) is a good alternative to other triptans since it's less likely to cause side effects and if other triptans haven't worked for you.
  • Available as a generic, which makes it cheaper than other medicines and is more likely to be covered by insurances.
  • Amerge (naratriptan) comes in two different strengths.
  • Ergomar (ergotamine) works better than other medicines if your migraines last more than 2 days or if you have more frequent migraines.
Downsides and risks
  • Amerge (naratriptan) is only available as a pill that must be swallowed, so it might not be good if you have trouble swallowing when you have a migraine.
  • Unlike other migraine medications, you have to wait for 4 hours before you can take the second dose of Amerge (naratriptan).
  • Amerge (naratriptan) is not as good as other medications for treating nausea that can happen with migraines.
  • Harmful to the fetus so avoid if you're pregnant or think you may be pregnant.
  • Doesn't prevent migraines from happening. It can only relieve them.
  • Excessive use can be dangerous and result in rebound headaches. Talk to your doctor if your headaches are worse and occurring more frequently.
  • May not be right for you if you have high blood pressure or had a heart attack.
Tips from our pharmacists for people taking the medication
  • Amerge (naratriptan) can only treat a migraine that's already happening. Amerge (naratriptan) doesn't prevent migraines.
  • Take Amerge (naratriptan) at the first sign of a migraine. You can take another dose if you don't feel better after 4 hours. Don't take more than two doses every 24 hours.
  • Amerge (naratriptan) can make you feel dizzy or tired when you first start taking it. Don't drive or do anything that requires concentration until you know how your body reacts to it.
  • If you finish the entire month's supply of Amerge (naratriptan) before it's time for your next refill, or if you have more than 4 migraines a month, talk to your doctor to see if you should try something else.
  • Amerge (naratriptan) can cause nausea or tightness in the chest or throat. Talk to your doctor if it bothers you.
  • Avoid if you're pregnant or think you may be pregnant since it can harm the fetus.
  • Take as soon as you feel the migraine coming on.
  • You may be more sensitive to cold since Ergomar (ergotamine) affects the circulation of your blood. Dress warmly.
  • Don't use Ergomar (ergotamine) excessively. The most you can take is 3 tablets per day or 5 tablets per week.
  • Don't use with triptans if you're taking Ergomar (ergotamine).
  • Talk to your doctor if you have heart disease or blood vessel problems before starting Ergomar (ergotamine).
Learn more
More about AmergeSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Amerge (naratriptan)?
Worth itNot sureNot worth it
More about ergotamineSide effectsAlternativesFDA package insert
Have you used Ergomar (ergotamine)?
Worth itNot sureNot worth it