Compare Amiloride vs. Aldactone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coming soon.

Midamor
(Amiloride)

Aldactone
(Spironolactone)

Coming soon.Removes extra water from your body. Aldactone (Spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.
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Reviews & ratings
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Have you used Midamor (Amiloride)?
Worth itNot sureNot worth it

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Have you used Aldactone (Spironolactone)?
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Side effects
AmilorideAldactone

We haven’t found good data for Amiloride side effects.

FDA side effect reports for Amiloride »

The Aldactone FDA package insert doesn’t have numbers about how common side effects are.

More about Aldactone side effects »
How it works
AmilorideAldactone
Coming soon.Aldactone (Spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.
Type of medication
AmilorideAldactone
Coming soon.
Antihypertensive
Aldosterone antagonist
Prescription only
Available as
AmilorideAldactone
  • Pill
  • Pill
Used for (click to learn more)
AmilorideAldactone
  • Congestive heart failure Hypertension
Risk factors for serious side effects
AmilorideAldactone
  • Taking with alcohol
  • Taking other medicines that lower your blood pressure
  • Current kidney problems
  • Taking other medicines that increase potassium
  • Use of salt substitutes
Detailed risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
AmilorideAldactone
No kidneys and liver related info.
  • You'll need to have blood tests done regularly since Aldactone (Spironolactone) can affect your potassium levels and kidneys.
Pain
AmilorideAldactone
No pain related info.
  • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
Upsides and benefits
AmilorideAldactone
Coming soon
  • Has a low risk of causing muscle problems from low potassium levels in your blood.
  • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
  • Can lower blood pressure.
  • Reduces the risk of death in people with heart failure.
Downsides and risks
AmilorideAldactone
Coming soon
  • Aldactone (Spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
  • Has many possible side effects, especially when higher doses are used.
  • Can increase the risk of tumor growth.
  • You'll need to have blood tests done regularly since Aldactone (Spironolactone) can affect your potassium levels and kidneys.
Tips from our pharmacists for people taking the medication
AmilorideAldactone
Coming soon
  • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
  • Don't use supplements or salt substitutes that are high in potassium.
  • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
  • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
  • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
Learn more
More about AmilorideSide effectsFDA package insert
Have you used Midamor (Amiloride)?
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More about AldactoneSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Aldactone (Spironolactone)?
Worth itNot sureNot worth it