Compare Amiloride vs. spironolactone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Midamor
(amiloride)

Aldactone
(spironolactone)

Coming soon.Removes extra water from your body. Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure.
Reviews & ratings
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Have you used Midamor (amiloride)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Aldactone (spironolactone)?
Worth itNot sureNot worth it
Side effects
Amiloridespironolactone

We haven’t found good data for Amiloride side effects.

FDA side effect reports for Amiloride »

The spironolactone FDA package insert doesn’t have numbers about how common side effects are.

More about spironolactone side effects »
How it works
Amiloridespironolactone
Coming soon.Aldactone (spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.
Type of medication
Amiloridespironolactone
Prescription only
Available as
Amiloridespironolactone
  • Pill
  • Pill
Used for
Amiloridespironolactone
  • Congestive Heart Failure Hypertension
Risk factors for serious side effects
Amiloridespironolactone
    Coming soon.
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
    • Current kidney problems
    • Taking other medicines that increase potassium
    • Use of salt substitutes
    Detailed Aldactone (spironolactone) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Kidneys and liver
    Amiloridespironolactone
    No kidneys and liver related info.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    Pain
    Amiloridespironolactone
    No pain related info.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    Upsides and benefits
    Amiloridespironolactone
    Coming soon
    • Has a low risk of causing muscle problems from low potassium levels in your blood.
    • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
    • Can lower blood pressure.
    • Reduces the risk of death in people with heart failure.
    Downsides and risks
    Amiloridespironolactone
    Coming soon
    • Aldactone (spironolactone) doesn't work well on its own. It should be used with another drug to help get rid of excess fluids.
    • Has many possible side effects, especially when higher doses are used.
    • Can increase the risk of tumor growth.
    • You'll need to have blood tests done regularly since Aldactone (spironolactone) can affect your potassium levels and kidneys.
    Tips from our pharmacists for people taking the medication
    Amiloridespironolactone
    Coming soon
    • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
    • Don't use supplements or salt substitutes that are high in potassium.
    • It can cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    • Tell your doctor about any muscle weakness, skin changes, and red or black tarry stool.
    • You will urinate more often within 2 to 3 days, and will have lower blood pressure in 2 to 3 weeks.
    Learn more
    More about AmilorideSide effectsFDA package insert
    Have you used Midamor (amiloride)?
    Worth itNot sureNot worth it
    More about spironolactoneSide effectsAlternativesFDA package insert
    Have you used Aldactone (spironolactone)?
    Worth itNot sureNot worth it