Compare amiloride vs. Aldactone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Midamor
(Amiloride)

Aldactone
(Spironolactone)

Coming soon.Removes extra water from your body. Aldactone (Spironolactone) is helpful when added to another diuretic to get rid of excess fluid in your body. Doesn't work well on its own.
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Reviews & ratings
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Side effects
amilorideAldactone

We haven’t found good data for amiloride side effects.

FDA side effect reports for amiloride »

We haven’t found good data for Aldactone side effects.

FDA side effect reports for Aldactone »
How it works
amilorideAldactone
Coming soon.Aldactone (Spironolactone) is a potassium-sparing diuretic that blocks aldosterone (a hormone) and helps the kidney get rid of excess fluids in your body.
Type of medication
amilorideAldactone
Coming soon.
Antihypertensive
Diuretic
Prescription only
Available as
amilorideAldactone
  • Pill
  • Pill
Used for (click to learn more)
amilorideAldactone
  • Congestive heart failure Hypertension
Risk factors for serious side effects
amilorideAldactone
Coming soon.
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
      Detailed Aldactone (Spironolactone) risks & warnings »
      Pregnancy category
      amilorideAldactone
      BFDA pregnancy category (Probably safe)

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.No specific alcohol-related info.
      Food
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.
      • Needs to have blood tests done to monitor electrolyte levels and kidney function.
      • Aldactone (Spironolactone) can increase the amount of potassium in your body. High potassium can cause heart problems. Baseline and routine blood tests are needed to monitor your potassium and kidney function.
      Sex
      No specific sex-related info.
      • You can have breast pain/swelling, irregular periods (women), or trouble with sexual performance.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      amilorideAldactone
      Coming soon.
      • Has a low risk of causing muscle problems due to low potassium levels in your blood.
      • More useful when taken with another diuretic that'll also help your body get rid of extra fluids.
      • Can lower blood pressure.
      • Reduces the risk of death in people with heart failure.
      Downsides and risks
      amilorideAldactone
      Coming soon.
      • Not very good at getting rid of excess fluids on its own. Should be used with another drug to help get rid of excess fluids.
      • Has many possible side effects, especially when higher doses are used.
      • Can increase the risk of tumor growth.
      • Needs to have blood tests done to monitor electrolyte levels and kidney function.
      Tips from our pharmacists for people taking the medication
      amilorideAldactone
      Coming soon.
      • Can make you dizzy or cause trouble concentrating, so be careful using it until you know how the medicine affects you.
      • Don't use supplements or salt substitutes that are high in potassium.
      • You can have breast pain/swelling, irregular periods (women), or trouble with sexual performance.
      • Tell your doctor about any muscle weakness, skin changes, red or black tarry stool.
      • Can take 2 to 3 days to see full diuretic effects and 2 to 3 weeks to see blood pressure lowering effects.
      Learn more
      More about amilorideSide effectsFDA package insert
      More about AldactoneSide effectsReviews & ratingsAlternativesFDA package insert