Compare amoxapine vs. Vivactil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Asendin
(amoxapine)

Vivactil
(protriptyline)

Stabilizes your mood. While Asendin (amoxapine) can treat depression, you have to take it several times a day and it can make you feel sleepy.Coming soon.
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Coupons for amoxapine
Best available price for 30 (50mg) tablets of amoxapine
Coupons for Vivactil
Best available price for 60 (5mg) tablets of protriptyline
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
Reviews for Asendin (amoxapine)
Not enough review data. Review it!
of people (All ages) say Asendin (amoxapine) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Asendin (amoxapine)?
Worth itNot sureNot worth it
Reviews for Vivactil (protriptyline)
Not enough review data. Review it!
+100% better vs. Asendin (amoxapine)
Not enough review data. Review it!
+100% better vs. Asendin (amoxapine)
Not enough review data. Review it!
+100% better vs. Asendin (amoxapine)
Have you used Vivactil (protriptyline)?
Worth itNot sureNot worth it
Side effects
amoxapineVivactil
  • Drowsiness or fatigue 14%
  • Dry mouth 14%
  • Constipation 12%
  • Vision changes 7%
More amoxapine side effects »

We haven’t found good data for Vivactil side effects.

FDA side effect reports for Vivactil »
How it works
amoxapineVivactil
Asendin (amoxapine) is a tricyclic antidepressant. It increases the activity of serotonin and norepinephrine in your brain which regulate your mood.Coming soon.
Type of medication
amoxapineVivactil
Prescription only
Available as
amoxapineVivactil
  • Pill
  • Pill
Used for
amoxapineVivactil
  • Depression
Risk factors for serious side effects
amoxapineVivactil
  • People under age 24
  • Glaucoma
  • Taking antidepressants
  • Taking opioids for pain relief or medicines for anxiety
  • Over age 65
Detailed Asendin (amoxapine) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Food
    amoxapineVivactil
    • Take Asendin (amoxapine) with food to avoid stomach upset.
    No food related info.
    Sleep
    amoxapineVivactil
    • You can feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
    No sleep related info.
    Upsides and benefits
    amoxapineVivactil
    • Asendin (amoxapine) can be used to treat more severe forms of depression.
    • Compared to similar medicines, Asendin (amoxapine) improves the mood in depression more quickly.
    • Asendin (amoxapine) is available as generic.
    Coming soon
    Downsides and risks
    amoxapineVivactil
    • Asendin (amoxapine) is not a first choice medicine for depression because of side effects.
    • In some people, Asendin (amoxapine) can stop working as early as 2-3 months after you start taking it.
    • Not recommended in older people, children under 16, or people who've had a history of seizures.
    Coming soon
    Tips from our pharmacists for people taking the medication
    amoxapineVivactil
    • You can feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
    • You might not notice any changes in your mood for at least a few weeks.
    • Take Asendin (amoxapine) with food to avoid stomach upset.
    • You're more likely to be dehydrated and constipated. Drink plenty of fluids and be careful not to get overheated if you're out in the sun.
    • Don't stop taking Asendin (amoxapine) without talking to your doctor. Stopping Asendin (amoxapine) suddenly can be very dangerous.
    Coming soon
    Learn more
    More about amoxapineSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Asendin (amoxapine)?
    Worth itNot sureNot worth it
    More about VivactilSide effectsReviews & ratingsFDA package insert
    Have you used Vivactil (protriptyline)?
    Worth itNot sureNot worth it