Compare amoxicillin vs. Bactrim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Amoxil (amoxicillin)

Prescription only
Treats bacterial infections.

Amoxil (amoxicillin) is a good and cheap antibiotic that comes in different forms to treat many types of bacterial infections.

5.0/ 7 average rating with 786 reviewsforamoxicillin
Kills bacteria.

Bactrim (sulfamethoxazole / trimethoprim) is good for treating many bacterial infections and is available as a generic. However, you can be more likely to sunburn.

5.0/ 7 average rating with 473 reviewsforBactrim
Upsides
  • First choice medicine to treat many bacterial infections.
  • Available in generic.
  • Available in different forms: tablet, capsule, and liquid. The liquid comes in many different flavors to make it taste better for people who don't like pills.
  • Side effects are generally not too bad compared to other antibiotics.
  • Widely available as a generic product and in a variety of formulations (tablet, capsule, suspension).
  • Works well to treat many types of bacterial infections
Downsides
  • While Amoxil (amoxicillin) can be used to treat different bacterial infections, many don't respond to it.
  • Can cause diarrhea, nausea, and vomiting.
  • Except for the extended-release form, you have to take Amoxil (amoxicillin) 2 to 3 times a day, which can be hard to remember.
  • The extended-release form can be more expensive because it's a brand name.
  • Makes you sensitive to the sun.
  • Can upset your stomach
  • Drink plenty of water or fluids to avoid harming your kidneys
  • May cause birth defects
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Extended-release tablet
  • Liquid
  • Pill
  • Liquid
Price
Lowest price near you
$4
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Lowest price near you
$4
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Reviews
786 
62%
think this treatment is worth it
45%
think this treatment works well
14%
think this treatment is a hassle

Have you used Amoxil (amoxicillin)?

Leave a review
473 
59%
think this treatment is worth it
49%
think this treatment works well
22%
think this treatment is a hassle

Have you used Bactrim (sulfamethoxazole / trimethoprim)?

Leave a review
Side effects
The Amoxil (amoxicillin) FDA package insert doesn’t have numbers about how common side effects are.
The Bactrim (sulfamethoxazole / trimethoprim) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Interaction with birth control

    Using oral birth control pills

  • Severe diarrhea

    Taking Amoxil (amoxicillin) for a long time

  • Severe allergic reaction

    History of penicillin allergies

  • New infections while taking Amoxil (amoxicillin)

    Weakened immune system

    ...and 1 more risk factors

  • Rash

    Mononucleosis

See more detailed risks and warnings
  • Lower kidney function

    Elderly

    ...and 1 more risk factors

See more detailed risks and warnings