Compare amoxicillin vs. Benzamycin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Amoxil
(amoxicillin)

Benzamycin
(benzoyl peroxide / erythromycin)

Treats bacterial infections. Amoxil (amoxicillin) is a good and cheap antibiotic that comes in different forms to treat many types of bacterial infections.Topical treatment for acne. Benzamycin (Benzoyl Peroxide / Erythromycin) is a topical combination acne treatment that may work better for people who didn't see an improvement when taking either medicine alone or simply don't want to take pill medication. You need to be careful because it can bleach your hair, clothing and other fabrics. It also needs to be stored in the refrigerator and is only good for three months..
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Reviews & ratings
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5amoxicillin
Reviews for Amoxil (amoxicillin)
62%
of people (All ages) say Amoxil (amoxicillin) is worth it
45%
say it works well
14%
say it's a big hassle
786 reviews
Have you used Amoxil (amoxicillin)?
Worth itNot sureNot worth it
Reviews for Benzamycin (benzoyl peroxide / erythromycin)
54%
-8% worse vs. Amoxil (amoxicillin)
26%
-19% worse vs. Amoxil (amoxicillin)
12%
+2% better vs. Amoxil (amoxicillin)
146 reviews
Have you used Benzamycin (benzoyl peroxide / erythromycin)?
Worth itNot sureNot worth it
Side effects
amoxicillinBenzamycin

The amoxicillin FDA package insert doesn’t have numbers about how common side effects are.

More about amoxicillin side effects »
  • Dyness 3%
  • Urticarial reaction 3%
More Benzamycin side effects »
How it works
amoxicillinBenzamycin
Amoxil (amoxicillin) is an antibiotic. It kills bacteria, and prevents them from reproducing and making their own protective covering.Benzamycin (Benzoyl Peroxide / Erythromycin) is a combination topical medicine. Erythromycin (an antibiotic) kills bacteria that cause acne. Benzoyl peroxide works to fight the bacteria and shed acne-affected skin.
Type of medication
amoxicillinBenzamycin
Prescription only
Prescription only
Available as
amoxicillinBenzamycin
  • Pill
  • Chewable tablet
  • Extended-release tablet
  • Liquid
  • Cream, gel, or ointment
Used for
amoxicillinBenzamycin
Risk factors for serious side effects
amoxicillinBenzamycin
  • Taking Amoxil (amoxicillin) for a long time
  • Weakened immune system
  • Not taking Amoxil (amoxicillin) correctly
  • History of penicillin allergies
  • Using oral birth control pills
  • Mononucleosis
Detailed Amoxil (amoxicillin) risks & warnings »
    • Using other medicines or products that irritate the skin
    • Eczema
    • Extreme temperatures (hot or cold)
      • Long-term use of Benzamycin (Benzoyl Peroxide / Erythromycin)
      Detailed Benzamycin (benzoyl peroxide / erythromycin) risks & warnings »
      Pregnancy

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Food
      amoxicillinBenzamycin
      • Take with food to prevent upset stomach. If you're taking the extended-release version, take within 1 hour of finishing your meal.
      No food related info.
      Pain
      amoxicillinBenzamycin
      No pain related info.
      • Let your doctor know if you notice abdominal discomfort, pain or diarrhea after starting this medicine.
      Weight
      amoxicillinBenzamycin
      No weight related info.
      • Not the best choice if you're pregnant. Benzamycin is categorized as pregnancy Category C (weight risks vs benefits) because of the benzoyl peroxide part.
      Upsides and benefits
      amoxicillinBenzamycin
      • First choice medicine to treat many bacterial infections.
      • Available in generic.
      • Available in different forms: tablet, capsule, and liquid. The liquid comes in many different flavors to make it taste better for people who don't like pills.
      • Side effects are generally not too bad compared to other antibiotics.
      • Benzamycin works better to reduce bacteria in oil glands and improve overall signs and symptoms of acne than either medicine alone.
      • Reduces bacteria on the skin, which "calms" the skin down (lowers the inflammatory response) in acne.
      • Combining an antibiotic with benzoyl peroxide lowers the chances of Benzamycin not working as well over time.
      • Although Benzamycin can irritate the skin, a true skin allergy is rare.
      • Can be used in combination with acne pill medicine if your doctor thinks you need it.
      Downsides and risks
      amoxicillinBenzamycin
      • While Amoxil (amoxicillin) can be used to treat different bacterial infections, many don't respond to it.
      • Can cause diarrhea, nausea, and vomiting.
      • Except for the extended-release form, you have to take Amoxil (amoxicillin) 2 to 3 times a day, which can be hard to remember.
      • The extended-release form can be more expensive because it's a brand name.
      • There's a risk of irritation with anything you apply to your skin and this is no different. Benzamycin, contains a topical antibiotic and can cause redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
      • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas
      • Can cause severe inflammation of the large intestine (pseudomembranous colitis).
      • Not the best choice if you're pregnant. Benzamycin is categorized as pregnancy Category C (weight risks vs benefits) because of the benzoyl peroxide part.
      • Can cause bleaching of hair and clothing.
      • You'll need to stay out of the sun or apply a sunscreen if you go outdoors.
      Tips from our pharmacists for people taking the medication
      amoxicillinBenzamycin
      • Finish all of the medicine, even if you start to feel better. Stopping Amoxil (amoxicillin) early can make the infection come back and harder to treat.
      • If you're on birth control, Amoxil (amoxicillin) might make it less effective. Talk to your doctor to see if you need to use backup.
      • Take with food to prevent upset stomach. If you're taking the extended-release version, take within 1 hour of finishing your meal.
      • If you have the liquid, keep the bottle in the fridge. The bottle is only good for 14 days after you pick it up. Shake the bottle well before using each dose.
      • You may have diarrhea or stomach upset when taking Amoxil (amoxicillin), but it should get better soon after you've finished. If the diarrhea gets worse, tell your doctor
      • Combination medicine you apply to your skin to treat acne.
      • Apply a thin film to clean and dry affected skin twice a day- in the morning and evening.
      • Store in the refrigerator, but don't freeze.
      • The pharmacist mixes the medicine when you pick it up at the drugstore. You'll need to use it within three months of this date or dispose of it properly.
      • Let your doctor know if you notice abdominal discomfort, pain or diarrhea after starting this medicine.
      • Using a moisturizer that doesn't block your pores (non-comedogenic) may help lessen common side effects of skin dryness and peeling.
      • Taking good care of your skin is an important part of treating acne. Lightly wash with warm water and non-soap-based or gentle cleanser.
      Learn more
      More about amoxicillinSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Amoxil (amoxicillin)?
      Worth itNot sureNot worth it
      More about BenzamycinSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Benzamycin (benzoyl peroxide / erythromycin)?
      Worth itNot sureNot worth it