Compare amoxicillin vs. Cipro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Amoxil (amoxicillin)

Prescription only

Cipro (ciprofloxacin)

Prescription only
Treats bacterial infections.

Amoxil (amoxicillin) is a good and cheap antibiotic that comes in different forms to treat many types of bacterial infections.

5.0/ 7 average rating with 786 reviewsforamoxicillin
Treats bacterial infections.

Cipro (ciprofloxacin) is a good, cheap antibiotic that treats many types of bacterial infections, but it interacts with some food and drugs.

5.2/ 7 average rating with 755 reviewsforCipro
Upsides
  • First choice medicine to treat many bacterial infections.
  • Available in generic.
  • Available in different forms: tablet, capsule, and liquid. The liquid comes in many different flavors to make it taste better for people who don't like pills.
  • Side effects are generally not too bad compared to other antibiotics.
  • Cipro (ciprofloxacin) is available in generic.
  • Cipro (ciprofloxacin) comes in different forms, including intravenous (IV) injection.
Downsides
  • While Amoxil (amoxicillin) can be used to treat different bacterial infections, many don't respond to it.
  • Can cause diarrhea, nausea, and vomiting.
  • Except for the extended-release form, you have to take Amoxil (amoxicillin) 2 to 3 times a day, which can be hard to remember.
  • The extended-release form can be more expensive because it's a brand name.
  • Cipro (ciprofloxacin) should be used with caution if you have kidney problems.
  • If you drink caffeine while on Cipro (ciprofloxacin), you may notice increased effects of the caffeine.
  • Some bacteria have developed resistance to Cipro (ciprofloxacin).
  • Cipro (ciprofloxacin) can interact with many other medications. Tell your doctor and pharmacist what medications, over-the-counter products, and supplements you are taking before starting Cipro (ciprofloxacin).
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Extended-release tablet
  • Liquid
  • Pill
  • Liquid
  • Injection
  • Extended release pill
Price
Lowest price near you
$4
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Reviews
786 
62%
think this treatment is worth it
45%
think this treatment works well
14%
think this treatment is a hassle

Have you used Amoxil (amoxicillin)?

Leave a review
755 
63%
think this treatment is worth it
53%
think this treatment works well
17%
think this treatment is a hassle

Have you used Cipro (ciprofloxacin)?

Leave a review
Side effects
The Amoxil (amoxicillin) FDA package insert doesn’t have numbers about how common side effects are.
2possible side effects
  • Nausea
    3%
  • Diarrhea
    2%
See more detailed side effects
Risks and warnings
  • Interaction with birth control

    Using oral birth control pills

  • Severe diarrhea

    Taking Amoxil (amoxicillin) for a long time

  • Severe allergic reaction

    History of penicillin allergies

  • New infections while taking Amoxil (amoxicillin)

    Weakened immune system

    ...and 1 more risk factors

  • Rash

    Mononucleosis

See more detailed risks and warnings
  • Tendon rupture

    People over age 60

    ...and 2 more risk factors

  • Myasthenia gravis

    Myasthenia gravis

  • Central nervous system effects

    Central nervous system disorders

    ...and 1 more risk factors

  • Heart rhythm problems

    Use with other QT prolonging drugs

    ...and 1 more risk factors

See more detailed risks and warnings