Compare amoxicillin vs. Minocycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Amoxil (amoxicillin)

Prescription only

Solodyn (Minocycline)

Prescription only
Treats bacterial infections.

Amoxil (amoxicillin) is a good and cheap antibiotic that comes in different forms to treat many types of bacterial infections.

5.0/ 7 average rating with 786 reviewsforamoxicillin
Treats bacterial infections.

Solodyn (Minocycline) is an effective way to treat certain skin infections, acne, and rosacea, but you'll need to use barrier methods of birth control since it can make birth control pills less effective and cause birth defects.

5.5/ 7 average rating with 17 reviewsforMinocycline
Upsides
  • First choice medicine to treat many bacterial infections.
  • Available in generic.
  • Available in different forms: tablet, capsule, and liquid. The liquid comes in many different flavors to make it taste better for people who don't like pills.
  • Side effects are generally not too bad compared to other antibiotics.
  • Clinical studies show it's effective against MRSA, a common skin infection, and it's commonly used to treat acne and rosacea.
  • Available as a generic, so it should be reasonably priced.
  • Solodyn (Minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Bacteria are less likely to become resistant to Solodyn (Minocycline) than other tetracycline antibiotics.
Downsides
  • While Amoxil (amoxicillin) can be used to treat different bacterial infections, many don't respond to it.
  • Can cause diarrhea, nausea, and vomiting.
  • Except for the extended-release form, you have to take Amoxil (amoxicillin) 2 to 3 times a day, which can be hard to remember.
  • The extended-release form can be more expensive because it's a brand name.
  • It can make birth control pills less effective, so people should use barrier methods of birth control like condoms or diaphragms while on Solodyn (Minocycline).
  • Can stain your teeth, mouth, and gums if you're using the tablets, or your skin if you're using the topical version, but this is temporary.
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Extended-release tablet
  • Liquid
  • Pill
  • Extended release
  • Extended release capsule
Price
Lowest price near you
$4
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Lowest price near you
$98.31
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Reviews
786 
62%
think this treatment is worth it
45%
think this treatment works well
14%
think this treatment is a hassle

Have you used Amoxil (amoxicillin)?

Leave a review
17 
53%
think this treatment is worth it
59%
think this treatment works well
18%
think this treatment is a hassle

Have you used Solodyn (Minocycline)?

Leave a review
Side effects
The Amoxil (amoxicillin) FDA package insert doesn’t have numbers about how common side effects are.
The Solodyn (Minocycline) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Interaction with birth control

    Using oral birth control pills

  • Severe diarrhea

    Taking Amoxil (amoxicillin) for a long time

  • Severe allergic reaction

    History of penicillin allergies

  • New infections while taking Amoxil (amoxicillin)

    Weakened immune system

    ...and 1 more risk factors

  • Rash

    Mononucleosis

See more detailed risks and warnings
  • Changes in teeth

    Age 8 years or younger

  • Decreased effectiveness of birth control pills

    Using oral birth control pills

  • Diarrhea from a superinfection (an infection that happens after, or in addition to, an earlier infection)

    Long antibiotic treatment period

  • Harm to fetus

    Women of childbearing age

See more detailed risks and warnings