Compare Androderm vs. Androgel

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Androderm
(Testosterone Patch)

Androgel
(Testosterone Gel)

Treats low testosterone. The testosterone patch is a topical form of hormone replacement that doesn't affect people you come in contact with, but it can cause skin irritation so you have to rotate its position every night.Treats low testosterone. This testosterone gel is a convenient topical form of hormone replacement, but you have to be careful about it rubbing off on other people. Also it can be cheaper than alternatives.
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Reviews & ratings
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Side effects
AndrodermAndrogel

The Androderm FDA package insert doesn’t have numbers about how common side effects are.

More about Androderm side effects »

The Androgel FDA package insert doesn’t have numbers about how common side effects are.

More about Androgel side effects »
How it works
AndrodermAndrogel
The testosterone patch works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.Testosterone gel works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
AndrodermAndrogel
Hormone replacement
Testosterone
Prescription only
Hormone replacement
Testosterone
Prescription only
Available as
AndrodermAndrogel
  • Patch
  • Cream, gel, or ointment
Used for (click to learn more)
AndrodermAndrogel
  • Low testosterone
  • Low testosterone
Risk factors for serious side effects
AndrodermAndrogel
Coming soon.Coming soon.
Pregnancy category
AndrodermAndrogel
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
XFDA pregnancy category (Unsafe)

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
  • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
AndrodermAndrogel
  • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
  • The testosterone patch prevents other people around you from coming in contact with testosterone, unlike other topical forms such as gels.
  • The testosterone patch only has to be placed once each night.
  • You put it on like a lotion, so it's very easy to apply.
  • Available in generic, so it's cheaper than some alternatives.
Downsides and risks
AndrodermAndrogel
  • Not available in generic.
  • You have to be careful to rotate the testosterone patch to a different part of your body each night.
  • Can cause skin irritation.
  • Has to be removed before you have an MRI.
  • The patch can become loose if you do heavy exercise or sweat a lot.
  • You have to make sure that you cover the area where you place testosterone gel after it's dry, otherwise it can rub off on people.
  • You have to wait at least 2 hours before you shower or swim after putting on Testosterone gel, otherwise your body won't absorb the entire amount.
Tips from our pharmacists for people taking the medication
AndrodermAndrogel
  • Place the testosterone patch on a clean, dry area of your skin each night. Don't put it on your scrotum or a bony part of your body.
  • Change the area where you place the testosterone patch every night, and wait at least 7 days before you put in on the same site again.
  • Make sure the patch is attached to your skin, especially along the edges. If it loosens, smooth the edges and then the center of the patch with your finger to make sure it's attached completely.
  • If the patch falls off before noon, apply another patch. If it falls off after that, don't apply another patch until your regular time at night. Don't use tape to keep the patch attached.
  • Don't bathe or swim for at least 3 hours after you put a new patch on. Also, heavy exercise or lots of sweating can make your patch fall off.
  • How to put it on: Don't put testosterone gel anywhere else except where you're taught by the doctor or pharmacist, usually the shoulders and upper arms. Don't put it around your genitals. Wash your hands with soap and water and dry them afterward. Cover the area with clothing as soon as it's dry so you don't spread it to other people.
  • Don't bathe or swim for at least 2 hours after you've put on testosterone gel so that it has time to absorb.
  • If you think you'll have skin-to-skin contact with someone else at the area where you've placed testosterone gel, wash that area with soap and water and dry. If someone else touches the area before you've washed it off, have them wash their skin with soap and water as soon as they can.
Learn more
More about AndrodermSide effectsReviews & ratingsAlternativesFDA package insert
More about AndrogelSide effectsReviews & ratingsAlternativesFDA package insert