Compare Androderm vs. Depo-Testosterone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats low testosterone.

The testosterone patch is a topical form of hormone replacement that doesn't affect people you come in contact with, but it can cause skin irritation so you have to rotate its position every night.

Treats low testosterone.

This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.

3.0/ 5 average rating with 100 reviewsforDepo-Testosterone
Upsides
  • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
  • The testosterone patch prevents other people around you from coming in contact with testosterone, unlike other topical forms such as gels.
  • The testosterone patch only has to be placed once each night.
  • A first-choice treatment for low testosterone in men and delayed puberty in boys.
  • Available in generic.
  • Only has to be given once every 2 to 4 weeks.
  • The shot can be done at home.
Downsides
  • Not available in generic.
  • You have to be careful to rotate the testosterone patch to a different part of your body each night.
  • Can cause skin irritation.
  • Has to be removed before you have an MRI.
  • The patch can become loose if you do heavy exercise or sweat a lot.
  • Only available as a shot.
  • Has to be given by someone else since it has to be injected into your buttocks.
Used for
  • Low testosterone
  • Low testosterone
Dosage forms
  • Patch
  • Injection
Price
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Reviews
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100 reviews so far
49%
saidit'sworth it
32%
saiditworked well
17%
saidit'sa big hassle

Have you used Depo-Testosterone (Testosterone Cypionate Injection)?

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Side effects
15possible side effects
  • Any appication site reaction
    28%
  • Application site pruritus
    17%
  • Application site vesicles
    6%
  • Back pain
    6%
  • Application site erythema
    3%
  • Application site exfoliation
    3%
  • Chills
    3%
  • Diarrhea
    3%
  • Fatigue
    3%
  • Gastroesophageal reflux disease
    3%
  • Hemarthrosis
    3%
  • Hematuria
    3%
  • Headache
    3%
  • Polyuria
    3%
  • Prostatitis
    3%
See more detailed side effects
The Depo-Testosterone (Testosterone Cypionate Injection) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
No information currently available
  • Breast tissue changes
    • Male
  • Changes in sex drive
    • Male
  • Inability to urinate
    • Enlarged prostate (benign prostatic hypertrophy)
  • Changes in sperm
    • Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)
  • Swelling in the legs
    • Heart, liver or kidney disease
  • High calcium in the blood
    • Inability to move
    • Cancer
  • Liver disease
  • Changes in mood
  • Changes in blood sugar
    • Diabetes
  • Changes in blood thinning
    • On blood thinners
  • Blood clots
See more detailed risks and warnings